Joachim Stephanie C
Universitäts-Augenklinik, Ruhr-Universität Bochum, Bochum.
Klin Monbl Augenheilkd. 2018 Feb;235(2):135-139. doi: 10.1055/s-0043-124085. Epub 2018 Feb 15.
Glaucoma is one of the most common causes for blindness worldwide. Even if some risk factors for this disease are known, like increased intraocular pressure or increased age, its pathomechanism is still not fully understood. Multiple studies recently analyzed the role of a Helicobacter pylori infection in the glaucoma pathogenesis. Several studies showed a correlation, while others did not come to this conclusion. In summary, it is very likely that a Helicobacter pylori infection coincides with an increased risk for a primary open-angle or normal-tension glaucoma. Still, larger studies, with strict inclusion and exclusion criteria, as well as age-matched control groups, are needed to find out if a Helicobacter pylori infection really leads to a higher risk for glaucoma.
青光眼是全球最常见的致盲原因之一。即使已知该疾病的一些风险因素,如眼压升高或年龄增长,但其发病机制仍未完全明确。最近多项研究分析了幽门螺杆菌感染在青光眼发病机制中的作用。一些研究显示存在相关性,而其他研究则未得出此结论。总之,幽门螺杆菌感染很可能与原发性开角型青光眼或正常眼压性青光眼的风险增加同时出现。不过,仍需要开展更大规模的研究,设定严格的纳入和排除标准,并设置年龄匹配的对照组,以确定幽门螺杆菌感染是否真的会导致青光眼风险升高。