在肾脏中成像纳米生物相互作用：深入了解纳米颗粒清除。
Imaging Nano-Bio Interactions in the Kidney: Toward a Better Understanding of Nanoparticle Clearance.
机构信息
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, Fujian, 361102, China.
出版信息
Angew Chem Int Ed Engl. 2018 Mar 12;57(12):3008-3010. doi: 10.1002/anie.201711705. Epub 2018 Feb 16.
All clear! Highlighted is work aimed at a better understanding of nano-bio interactions for rational design of renal-clearable nanoparticles in diseased kidneys. Renal clearance of ultra-small gold nanoparticles (AuNPs) is not only dependent upon the Choi criteria but is also affected by the microphysiological structure of the glomerular barrier and the pathophysiological changes in the nephron.
一切正常！突出显示的工作旨在更好地理解纳米 - 生物相互作用，从而合理设计用于病变肾脏的可经肾清除的纳米颗粒。超小金纳米颗粒（AuNPs）的肾脏清除不仅依赖于 Choi 标准，而且还受到肾小球屏障的微生理结构和肾单位的病理生理变化的影响。
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