Rühle Paul F, Klein Gerhart, Rung Tatiana, Tiep Phan Hong, Fournier Claudia, Fietkau Rainer, Gaipl Udo S, Frey Benjamin
a Department of Radiation Oncology , Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg , Erlangen , Germany.
b Practice for Cardiology , Bad Steben , Germany.
Mod Rheumatol. 2019 Jan;29(1):165-172. doi: 10.1080/14397595.2018.1442640. Epub 2018 Mar 2.
Therapies with low doses of radon have beneficial effects on patients suffering from chronic painful degenerative and inflammatory diseases. We already showed that this is accompanied by systemic immune modulations. We here focus on pain-reducing effects of very low doses of radon by adding carbon dioxide water and its impact on heart rate variability (HRV), blood pressure and free radicals.
97 of 103 patients receiving radon spa (1.200 Bq/l at 34 °C or 600 Bq/l, 1 g/l CO at 34 °C) were monitored before and at three different time points after therapy. Individual pain perception was analyzed and the capability to process radicals. At each time point, the hypertensive patients (n = 46) were examined over 24 h for blood pressure and HRV.
Long-term pain reduction was observed in the majority of patients. A modulation of superoxide dismutase was identified, presumably representing a priming effect for lowering radiation stress. Further, lowering of blood pressure, especially in those patients who additionally received carbon dioxide, was seen. Radon did in particular impact on HRV implying lasting relaxation effects.
Radon/carbon dioxide spa efficiently reduces pain. In particular, patients simultaneously suffering from painful and cardiovascular diseases should be treated by combination of radon and CO.
低剂量氡疗法对患有慢性疼痛性退行性和炎症性疾病的患者具有有益效果。我们已经表明，这伴随着全身免疫调节。在此，我们通过添加碳酸水来关注极低剂量氡的止痛效果及其对心率变异性（HRV）、血压和自由基的影响。
对103名接受氡温泉治疗（34℃时1200 Bq/l或600 Bq/l，34℃时1 g/l二氧化碳）的患者中的97名在治疗前和治疗后的三个不同时间点进行监测。分析个体疼痛感知和处理自由基的能力。在每个时间点，对46名高血压患者进行24小时的血压和HRV检查。
大多数患者出现长期疼痛减轻。发现超氧化物歧化酶有调节作用，推测这代表了降低辐射应激的启动效应。此外，观察到血压降低，尤其是在那些额外接受二氧化碳治疗的患者中。氡对HRV有特别影响，意味着有持久的放松效果。
氡/二氧化碳温泉能有效减轻疼痛。特别是，同时患有疼痛性疾病和心血管疾病的患者应采用氡和二氧化碳联合治疗。
