Li Na, Han Juntao, Hu Dahai, Cheng Jing, Wang Hongtao, Wang Yunchuan, Yang Xuekang, Liu Jiaqi, Li Ting, Zhao Wenli
a Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University , Xi'an, Shaanxi Province , China.
J Cosmet Laser Ther. 2018 Nov-Dec;20(7-8):436-441. doi: 10.1080/14764172.2017.1418517. Epub 2018 Feb 16.
Intense pulsed light (IPL) has been used to treat postinflammatory hyperpigmentation and telangiectasia in Fitzpatrick type I -II skin. However, its therapeutic effects after superficial second-degree burns in Asian populations with Fitzpatrick type III-IV skin are uncertain. Thirty-five Han Chinese patients with facial or hand hyperpigmentation and telangiectasia due to second-degree fire burns received treatment with IPL. Each patient underwent 2-6 treatments over 3-5 weeks. The laser wavelength was 560-615 nm. Skin pigmentation was evaluated by two plastic surgeons as well as by the patients themselves (self-evaluation) before treatment at the end of the treatment cycle and 1 year after the first treatment. Blood flow in telangiectasia skin was measured by laser Doppler flow. The results showed that IPL significantly lessened hyperpigmentation so that close to normal skin color was achieved after the treatment cycles, and pigmentation did not reoccur 1 year after the first treatment. Approximately 82.9% of the patients were satisfied with their treatment outcomes. There were no post-treatment complications. Doppler showed a significant decreased blood flow in telangiectasia after treatment. In conclusion, IPL is an effective and safe modality for Chinese patients with hyperpigmentation and telangiectasia after fire burns.
强脉冲光（IPL）已被用于治疗 Fitzpatrick Ⅰ-Ⅱ型皮肤的炎症后色素沉着和毛细血管扩张。然而，其对 Fitzpatrick Ⅲ-Ⅳ型皮肤的亚洲人群浅表二度烧伤后的治疗效果尚不确定。35 名因二度火烧伤导致面部或手部色素沉着和毛细血管扩张的汉族患者接受了 IPL 治疗。每位患者在 3-5 周内接受了 2-6 次治疗。激光波长为 560-615nm。在治疗周期结束时、首次治疗后 1 年，由两名整形外科医生以及患者本人（自我评估）对皮肤色素沉着进行评估。通过激光多普勒血流仪测量毛细血管扩张皮肤的血流。结果显示，IPL 显著减轻了色素沉着，以至于在治疗周期后接近正常肤色，且首次治疗后 1 年色素沉着未复发。约 82.9%的患者对治疗结果满意。治疗后无并发症。多普勒显示治疗后毛细血管扩张处血流显著减少。总之，对于火烧伤后色素沉着和毛细血管扩张的中国患者，IPL 是一种有效且安全的治疗方式。
