瑜伽治疗更年期症状的系统评价和荟萃分析。
Yoga for menopausal symptoms-A systematic review and meta-analysis.
机构信息
Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany; Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), Faculty of Health, University of Technology Sydney, Sydney, Australia.
Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), Faculty of Health, University of Technology Sydney, Sydney, Australia.
出版信息
Maturitas. 2018 Mar;109:13-25. doi: 10.1016/j.maturitas.2017.12.005. Epub 2017 Dec 6.
OBJECTIVES
To systematically review and meta-analyze the effectiveness of yoga for menopausal symptoms.
METHODS
Medline (via PubMed), the Cochrane Central Register of Controlled Trials, and Scopus were screened through to February 21, 2017 for randomized controlled trials (RCTs) comparing the effects of yoga on menopausal symptoms to those of no treatment or active comparators. Standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated. Two authors independently assessed risk of bias using the Cochrane risk of bias tool.
RESULTS
Thirteen RCTs with 1306 participants were included. Compared with no treatment, yoga reduced total menopausal symptoms (SMD=-1.05; 95% CI -1.57 to -0.53), psychological (SMD=-0.75; 95% CI -1.17 to -0.34), somatic (SMD=-0.65; 95% CI -1.05 to -0.25), vasomotor (SMD=-0.76; 95% CI -1.27 to -0.25), and urogenital symptoms (SMD=-0.53; 95% CI -0.81 to -0.25). Compared with exercise controls, only an effect on vasomotor symptoms was found (SMD=-0.45; 95% CI -0.87 to -0.04). Effects were robust against selection bias, but not against detection and attrition bias. No serious adverse events were reported.
CONCLUSION
Yoga seems to be effective and safe for reducing menopausal symptoms. Effects are comparable to those of other exercise interventions.
目的
系统评价和荟萃分析瑜伽对更年期症状的疗效。
方法
通过 Medline（通过 PubMed）、Cochrane 对照试验中心注册库和 Scopus 检索，截至 2017 年 2 月 21 日，纳入比较瑜伽对更年期症状疗效与无治疗或阳性对照比较的随机对照试验（RCT）。计算标准化均数差（SMD）和 95％置信区间（CI）。两名作者独立使用 Cochrane 偏倚风险工具评估偏倚风险。
结果
纳入 13 项 RCT 共计 1306 名参与者。与无治疗相比，瑜伽可降低更年期总症状（SMD=-1.05；95％CI-1.57 至-0.53）、心理症状（SMD=-0.75；95％CI-1.17 至-0.34）、躯体症状（SMD=-0.65；95％CI-1.05 至-0.25）、血管舒缩症状（SMD=-0.76；95％CI-1.27 至-0.25）和泌尿生殖系统症状（SMD=-0.53；95％CI-0.81 至-0.25）。与运动对照组相比，仅发现对血管舒缩症状有影响（SMD=-0.45；95％CI-0.87 至-0.04）。结果对选择偏倚具有稳健性，但对检测和失访偏倚不具有稳健性。未报告严重不良事件。
结论
瑜伽似乎对缓解更年期症状有效且安全。其效果可与其他运动干预相媲美。
Zotero 插件