1School of Economic and Business Sciences,University of the Witwatersrand,1 Jan Smuts Avenue,Braamfontein,Johannesburg 2000,South Africa.
2MRC Developmental Pathways for Health Research Unit,Faculty of Health Sciences,University of the Witwatersrand,Johannesburg,South Africa.
Public Health Nutr. 2018 Jul;21(10):1810-1818. doi: 10.1017/S1368980018000125. Epub 2018 Feb 19.
To estimate the determinants of stunting using rich data from a birth cohort study from urban South Africa and to examine the various mechanisms, both proximate and distal, through which maternal education affects stunting.
Multivariate regression analysis using birth cohort data, where the outcome variable was stunting at age 2 years, and multiple mediator analysis to identify pathways from maternal education to stunting.
South Africa's largest metropolitan area, Soweto-Johannesburg.
Participants of Birth to Twenty Plus, a longitudinal cohort study of children born in 1990 (n 691).
In multivariate analysis, the birth weight Z-score (-0·084; P<0·001; 95 % CI -0·11, -0·06), the mother's openness towards modern health care, captured by a vaccination score (-0·05; P=0·04; 95 % CI -0·10, -0·00), and a better-quality care environment (-0·015; P=0·04; 95 % CI -0·03, -0·00) were found to be negatively associated with stunting. Having experienced symptoms of illness related to ears and eyes increased the risk of stunting (0·038; P=0·01; 95 % CI 0·01, 0·07). Results of the mediation analysis showed that maternal education had an indirect effect on stunting largely through socio-economic status and the antenatal environment (measured by the birth weight Z-score).
Overall, many of the factors that were protective against stunting in the final analysis, whether they operated through maternal education or not, were related to the mother's contribution to the child's life. This reinforces the idea that to minimise stunting, enhanced antenatal and postnatal services to better support and empower mothers may be important.
利用南非城市出生队列研究的丰富数据,估计发育迟缓的决定因素,并检验母亲教育影响发育迟缓的各种近端和远端机制。
使用出生队列数据的多变量回归分析,因变量为 2 岁时发育迟缓,采用多中介分析确定母亲教育与发育迟缓之间的途径。
南非最大的都市区,索韦托-约翰内斯堡。
出生至二十加,一项对 1990 年出生的儿童进行的纵向队列研究的参与者(n=691)。
在多变量分析中,出生体重 Z 评分(-0.084;P<0.001;95%置信区间-0.11,-0.06)、母亲对现代医疗保健的开放程度,由疫苗评分(-0.05;P=0.04;95%置信区间-0.10,-0.00)和更好的护理环境(-0.015;P=0.04;95%置信区间-0.03,-0.00)与发育迟缓呈负相关。经历与耳朵和眼睛相关的疾病症状会增加发育迟缓的风险(0.038;P=0.01;95%置信区间 0.01,0.07)。中介分析的结果表明,母亲教育对发育迟缓的间接影响主要通过社会经济地位和产前环境(以出生体重 Z 评分衡量)。
总的来说,在最终分析中,许多保护因素免受发育迟缓的影响,无论是通过母亲教育还是其他因素,都与母亲对孩子生活的贡献有关。这进一步强化了这样一种观点,即要尽量减少发育迟缓,可能需要加强产前和产后服务,以更好地支持和增强母亲的能力。