原发性肺滑膜肉瘤的自发消退。

Spontaneous Regression of Primary Pulmonary Synovial Sarcoma.

机构信息

Division of Thoracic Surgery, Department of Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

Ann Thorac Surg. 2018 Mar;105(3):e129-e131. doi: 10.1016/j.athoracsur.2017.09.008.

DOI:10.1016/j.athoracsur.2017.09.008

PMID:29455826

Abstract

We report a rare case of primary pulmonary synovial sarcoma that underwent spontaneous regression after a transbronchial biopsy. A 38-year-old woman with a well-demarcated solitary mass shadow on chest roentgenogram was referred to us. A transbronchial biopsy was performed, and immunohistochemical results as well as detection of SYT-SSX1 (SYnovial sarcoma Translocation-Synovial Sarcoma X chromosome breakpoint) transcripts resulted in a diagnosis of synovial sarcoma. A right lower lobectomy was performed during video-assisted thoracoscopic surgery. Pathologic examination revealed widespread coagulative necrosis with feeding arterioles occluded by organized thrombi. To our knowledge, this is the first report of a case of spontaneous regression of primary pulmonary synovial sarcoma.

摘要

我们报告了一例罕见的原发性肺滑膜肉瘤病例，该病例在经支气管活检后自发消退。一名 38 岁女性因胸片上有界限清楚的单发肿块阴影而被转介给我们。进行了经支气管活检，免疫组织化学结果以及 SYT-SSX1（滑膜肉瘤易位-滑膜肉瘤 X 染色体断点）转录本的检测结果提示滑膜肉瘤的诊断。在电视辅助胸腔镜手术下进行了右下肺叶切除术。病理检查显示广泛的凝固性坏死，伴由机化血栓阻塞的滋养小动脉。据我们所知，这是首例原发性肺滑膜肉瘤自发消退的病例报告。