一项关于探索前列腺癌与2型糖尿病之间相互作用的文献系统综述。
A systematic review of the literature exploring the interplay between prostate cancer and type two diabetes mellitus.
作者信息
Crawley Danielle, Chamberlain Florence, Garmo Hans, Rudman Sarah, Zethelius Björn, Holmberg Lars, Adolfsson Jan, Stattin Par, Carroll Paul, Van Hemelrijck Mieke
机构信息
Translational Oncology and Urology Research Group, King's College London, London SE1 9RT, UK.
Department of Medical Oncology, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.
出版信息
Ecancermedicalscience. 2018 Jan 25;12:802. doi: 10.3332/ecancer.2018.802. eCollection 2018.
Prostate cancer (PCa) and type two diabetes mellitus (T2DM) are both increasing prevalent conditions and often occur concurrently. However, the relationship between the two is more complex than just two prevalent conditions co-existing. This review systematically explores the literature around the interplay between the two conditions. It covers the impact of pre-existing T2DM on PCa incidence, grade and stage, as well as exploring the impact of T2DM on PCa outcomes and mortality and the interaction between T2DM and PCa treatments.
前列腺癌（PCa）和2型糖尿病（T2DM）都是日益普遍的疾病，且常常同时发生。然而，两者之间的关系比仅仅是两种普遍疾病共存更为复杂。本综述系统地探讨了有关这两种疾病相互作用的文献。它涵盖了既往存在的T2DM对PCa发病率、分级和分期的影响，以及探讨T2DM对PCa预后和死亡率的影响，以及T2DM与PCa治疗之间的相互作用。
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