Radhouane Khaled, Bedioui Aziz, Yedeas Mohamed Dehmani, Zayet Souheil, Jebari Maroua, Yedeas Mondher, Harbaoui Ahmed, Chkili Ridha
Department of Neurosurgery, Military Hospital of Tunis, Université de Tunis El Manar, Tunisia.
Department of Infectious Diseases, University Hospital La Rabta, Université de Tunis El Manar, Tunisia.
IDCases. 2020 Oct 23;22:e00996. doi: 10.1016/j.idcr.2020.e00996. eCollection 2020.
Candida spp. brain abscess is scare. Clinical presentation is unspecific. Diagnosis requires mycological culture of a puncture or biopsy specimen. Therapeutic management is based on prolonged course of azole or liposomal amphotericin B. We reported the case of brain abscess in a 27 year-old female patient, with no past history and not secondary to candidemia. The fungus was isolated from a puncture of abscess with complete resection. The outcome was favorable under antifungal treatment by voriconazole.
念珠菌属脑脓肿较为罕见。临床表现无特异性。诊断需要对穿刺或活检标本进行真菌培养。治疗管理基于长期使用唑类药物或脂质体两性霉素B。我们报告了一例27岁女性脑脓肿病例，该患者无既往病史，且并非由念珠菌血症继发。通过脓肿穿刺并完整切除后分离出真菌。在伏立康唑抗真菌治疗下，预后良好。
