Ling Yuan, Xie Qing, Zhang Zikang, Zhang Hua
Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Institute of Laboratory Medicine, Guangdong Medical University, Dongguan, 523808 China.
Biomark Res. 2018 Feb 13;6:8. doi: 10.1186/s40364-018-0123-1. eCollection 2018.
Conventional treatments for acute leukemia include chemotherapy, radiation therapy, and intensive combined treatments (including bone marrow transplant or stem cell transplants). Novel treatment approaches are in active development. Recently, protein kinase inhibitors are on clinical trials and offer hope as new drugs for acute leukemia treatment. This review will provide a brief summary of the protein kinase inhibitors in clinical applications for acute leukemia treatment.
急性白血病的传统治疗方法包括化疗、放疗以及强化联合治疗（包括骨髓移植或干细胞移植）。新型治疗方法正在积极研发中。最近，蛋白激酶抑制剂正在进行临床试验，并有望成为治疗急性白血病的新药。本综述将简要总结蛋白激酶抑制剂在急性白血病治疗临床应用中的情况。
