Pal Pooja, Singh Bikramjit, Kane Shubhada, Chaturvedi Pankaj
1Head and Neck Services, Tata Memorial Hospital, Mumbai, India.
Present Address: Department of Otolaryngology and Head Neck Surgery, SGRD Hospital, Amritsar, India.
Indian J Otolaryngol Head Neck Surg. 2018 Mar;70(1):10-14. doi: 10.1007/s12070-017-1170-x. Epub 2017 Jul 19.
Though the association between follicular carcinoma and bone metastasis is well established, the site-wise distribution is not known. One hundred seventy-three patients of follicular carcinoma presenting between 2003 and 2011 were selected from 1093 patients of follicular lesions presenting at a single institution. Of these, 59 (34%) with bone metastasis were included in the study. Fifty of the 59 patients (84.7%) had metastasis at presentation, while 9 developed bone metastasis during follow-up. Sixty-one percent had solitary metastasis, 15 (25.4%) had multiple bone involvement, while 8 patients (13.6%) had synchronous lung metastasis. Overall, the spine was the commonest site of bone metastases, seen in 20 patients (33.9%), followed by the pelvis, skull, long bones and sternum. Bone metastasis is a known phenomenon in follicular carcinoma. The spine is the commonest site followed by the pelvis.
虽然滤泡状癌与骨转移之间的关联已得到充分证实，但骨转移的部位分布尚不清楚。从某一机构就诊的1093例滤泡状病变患者中，选取了2003年至2011年间就诊的173例滤泡状癌患者。其中，59例（34%）发生骨转移的患者被纳入研究。59例患者中有50例（84.7%）在就诊时即有转移，而9例在随访期间发生骨转移。61%为单发转移，15例（25.4%）有多发性骨受累，8例（13.6%）有同步肺转移。总体而言，脊柱是骨转移最常见的部位，20例（33.9%）出现，其次是骨盆、颅骨、长骨和胸骨。骨转移在滤泡状癌中是一种已知现象。脊柱是最常见的部位，其次是骨盆。
