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一例二氧化碳监测仪有助于诊断使用舒更葡糖钠后发生喉痉挛的病例。

A case in which a capnometer was useful for diagnosing laryngospasm following administration of sugammadex.

作者信息

Kou Keito, Omae Takeshi, Wakabayashi Saiko, Sakuraba Sonoko

机构信息

Department of Anesthesiology and Pain Clinic, Juntendo University Shizuoka hospital, 1129 Izunokuni, Shizuoka, Japan.

出版信息

JA Clin Rep. 2017;3(1):41. doi: 10.1186/s40981-017-0111-8. Epub 2017 Aug 15.

Abstract

BACKGROUND

Sugammadex has been reported to cause upper-airway obstruction, such as laryngospasm or bronchospasm. These two conditions are treated using different approaches, but the differential diagnosis is difficult.

CASE PRESENTATION

We describe a case in which general anesthesia was administered via endotracheal intubation, in combination with brachial-plexus block, for arthroscopic surgical treatment of a rotator-cuff tear caused by recurrent shoulder dislocation. The total dose of rocuronium administered was 90 mg, and the last dose of 10 mg was given 15 min before the end of the surgery. Sugammadex was intravenously administered at 100 mg to reverse the effect of rocuronium after the operation ended. After extubation in this case, we placed a mask firmly around the patient's mouth, and thus, there was no air leakage around the mask. We detected upper-airway obstruction that was presumably attributable to administration of sugammadex. The end-tidal carbon dioxide (EtCO) concentration was undetectable on a capnometer. Although 100% oxygen was administered at 10 L/min via a facemask, oxygen saturation (SpO) decreased to approximately 70%. With suspected onset of laryngospasm, continuous positive airway pressure with 100% oxygen at 10 L/min was started at 30 cm HO. The patient's airway obstruction resolved after a short time.

CONCLUSION

The use of a capnometer facilitated the diagnosis of laryngospasm and allowed us to administer appropriate treatment after administration of sugammadex.

摘要

背景

据报道,舒更葡糖钠可导致上呼吸道梗阻,如喉痉挛或支气管痉挛。这两种情况的治疗方法不同,但鉴别诊断困难。

病例报告

我们描述了一例因复发性肩关节脱位导致肩袖撕裂,在关节镜手术治疗中采用气管插管全身麻醉联合臂丛神经阻滞的病例。罗库溴铵的总给药剂量为90mg,最后10mg剂量在手术结束前15分钟给予。术后静脉注射100mg舒更葡糖钠以逆转罗库溴铵的作用。该病例拔管后,我们将面罩紧紧地罩在患者嘴上,因此面罩周围没有漏气。我们检测到可能归因于舒更葡糖钠给药的上呼吸道梗阻。在二氧化碳监测仪上未检测到呼气末二氧化碳(EtCO)浓度。尽管通过面罩以10L/min的速度给予100%氧气,但氧饱和度(SpO)降至约70%。怀疑发生喉痉挛后,开始以30cmH₂O的压力持续给予100%氧气并进行气道正压通气。患者的气道梗阻在短时间后得到缓解。

结论

使用二氧化碳监测仪有助于喉痉挛的诊断,并使我们能够在给予舒更葡糖钠后进行适当的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3291/6967178/e11f766304fa/40981_2017_111_Fig1_HTML.jpg

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