Ribaldone Davide G, Mazzucco Dario, Fagoonee Sharmila, Crocellà Lucia, Lavagna Alessandro, Fracchia Mario, Caviglia Gian P, Simondi Daniele, Rocca Rodolfo, Astegiano Marco
Division of Gastroenterology, Department of Medical Sciences, University of Turin, Turin, Italy -
Division of Gastroenterology, Ospedale degli Infermi, Rivoli, Turin, Italy.
Minerva Gastroenterol Dietol. 2018 Sep;64(3):235-250. doi: 10.23736/S1121-421X.18.02483-2. Epub 2018 Feb 19.
Helicobacter pylori (H. pylori) is a Gram-negative bacterium, usually acquired during childhood, whose natural habitat is the gastric lumen. H. pylori is accepted as the most important cause of gastritis and peptic ulcer in humans. Nevertheless, its important role in the pathogenesis of gastric cancer as well as in several extra-gastroduodenal diseases has been confirmed. The aim of this work is to discuss, for the first time in a single article, all publications concerning H. pylori infection arising from Piedmont region, Italy, where in 1893 Giulio Bizzozero was the first who observed and described spiral organisms in the stomach of animal models. A systematic review of all publications on the management of H. pylori in adults in Piedmont, based on a PubMed and a Scopus research from 1965 to 2017 was performed. The discussed aspects are the epidemiology, the study on gastric and extragastric diseases related to H. pylori, the diagnostic methods, the treatment of H. pylori infection, and the possibility of reinfection. In conclusions, with almost 70 publications, Piedmont has proudly maintained the tradition of the father of the H. pylori.
幽门螺杆菌（H. pylori）是一种革兰氏阴性菌，通常在儿童时期感染，其自然栖息地是胃腔。幽门螺杆菌被认为是人类胃炎和消化性溃疡的最重要病因。然而，其在胃癌发病机制以及几种胃十二指肠外疾病中的重要作用已得到证实。本文的目的是在一篇文章中首次讨论来自意大利皮埃蒙特地区所有关于幽门螺杆菌感染的出版物，1893年朱利奥·比佐泽罗（Giulio Bizzozero）是第一个在动物模型胃中观察并描述螺旋形生物体的人。基于1965年至2017年在PubMed和Scopus上的研究，对皮埃蒙特地区成人幽门螺杆菌管理的所有出版物进行了系统综述。讨论的方面包括流行病学、与幽门螺杆菌相关的胃和胃外疾病研究、诊断方法、幽门螺杆菌感染的治疗以及再次感染的可能性。总之，皮埃蒙特地区有近70篇出版物，自豪地保持了幽门螺杆菌之父的传统。
