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心脏流体动力学与形变成像相结合。

Cardiac fluid dynamics meets deformation imaging.

作者信息

Dal Ferro Matteo, Stolfo Davide, De Paris Valerio, Lesizza Pierluigi, Korcova Renata, Collia Dario, Tonti Giovanni, Sinagra Gianfranco, Pedrizzetti Gianni

机构信息

Cardiovascular Department, Azienda Ospedaliera Universitaria Integrata of Trieste, Trieste, Italy.

Department of Engineering and Architecture, University of Trieste, P.le Europa 1, 34127, Trieste, Italy.

出版信息

Cardiovasc Ultrasound. 2018 Feb 20;16(1):4. doi: 10.1186/s12947-018-0122-2.

DOI:10.1186/s12947-018-0122-2
PMID:29458381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5819081/
Abstract

Cardiac function is about creating and sustaining blood in motion. This is achieved through a proper sequence of myocardial deformation whose final goal is that of creating flow. Deformation imaging provided valuable contributions to understanding cardiac mechanics; more recently, several studies evidenced the existence of an intimate relationship between cardiac function and intra-ventricular fluid dynamics. This paper summarizes the recent advances in cardiac flow evaluations, highlighting its relationship with heart wall mechanics assessed through the newest techniques of deformation imaging and finally providing an opinion of the most promising clinical perspectives of this emerging field. It will be shown how fluid dynamics can integrate volumetric and deformation assessments to provide a further level of knowledge of cardiac mechanics.

摘要

心脏功能在于使血液流动并维持其流动状态。这是通过心肌变形的适当顺序来实现的,其最终目标是产生血流。变形成像为理解心脏力学做出了重要贡献;最近,多项研究证实了心脏功能与心室内流体动力学之间存在密切关系。本文总结了心脏血流评估的最新进展,强调了其与通过最新变形成像技术评估的心脏壁力学之间的关系,并最终对这一新兴领域最具前景的临床前景发表了看法。将展示流体动力学如何整合容积和变形评估,以提供对心脏力学更深层次的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/5a3b9c3b2bc6/12947_2018_122_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/49e6d3f3bb13/12947_2018_122_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/a544ec72b399/12947_2018_122_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/b7c38f065e23/12947_2018_122_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/88dea0209991/12947_2018_122_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/2456639c7b10/12947_2018_122_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/87a8f85569ad/12947_2018_122_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/5a3b9c3b2bc6/12947_2018_122_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/49e6d3f3bb13/12947_2018_122_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/a544ec72b399/12947_2018_122_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/b7c38f065e23/12947_2018_122_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/88dea0209991/12947_2018_122_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/2456639c7b10/12947_2018_122_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/87a8f85569ad/12947_2018_122_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6476/5819081/5a3b9c3b2bc6/12947_2018_122_Fig7_HTML.jpg

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J Am Coll Cardiol. 2017 Aug 22;70(8):942-954. doi: 10.1016/j.jacc.2017.06.046.
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On estimating intraventricular hemodynamic forces from endocardial dynamics: A comparative study with 4D flow MRI.从心内膜动力学估计心室内血流动力学力:与4D流动MRI的比较研究
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Left ventricular hemodynamic forces as a marker of mechanical dyssynchrony in heart failure patients with left bundle branch block.
Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke.
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