Mandy S H
J Am Acad Dermatol. 1986 Oct;15(4 Pt 2):878-9, 888-9. doi: 10.1016/s0190-9622(86)70245-4.
Full-face or half-face dermabrasions for acne scarring were performed in 123 patients, 88 of whom received pretreatment for at least 2 weeks with 0.05% tretinoin cream. In the group that received tretinoin, healing, as evidenced by reepithelialization, was complete by 7 days; most of these patients completely healed in 5 days. All patients who did not receive tretinoin healed by 11 days, but none healed sooner than 7 days. No milia or postinflammatory hyperpigmentation was experienced by patients treated with tretinoin when the drug was resumed within 1 week after dermabrasion. In the group that received no tretinoin, milia and postinflammatory hyperpigmentation occurred in 28% of patients postoperatively.
对123例痤疮瘢痕患者进行了全脸或半脸皮肤磨削术，其中88例患者用0.05%维甲酸乳膏预处理至少2周。在接受维甲酸治疗的组中，上皮再形成证明愈合在7天内完成；这些患者大多数在5天内完全愈合。所有未接受维甲酸治疗的患者在11天内愈合，但无一例早于7天愈合。在皮肤磨削术后1周内恢复使用维甲酸治疗的患者未出现粟丘疹或炎症后色素沉着。在未接受维甲酸治疗的组中，28%的患者术后出现粟丘疹和炎症后色素沉着。
