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Screening for Adult Attention-Deficit/Hyperactivity Disorder in a Psychiatric Outpatient Population with Specific Focus on Sex Differences.针对精神科门诊患者群体进行成人注意力缺陷多动障碍筛查,特别关注性别差异。
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2
The effectiveness of behavioural and cognitive behavioural therapies for insomnia on depressive and fatigue symptoms: A systematic review and network meta-analysis.行为和认知行为疗法治疗失眠对抑郁和疲劳症状的效果:系统评价和网络荟萃分析。
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3
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4
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The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys.世界卫生组织世界心理健康调查中《精神疾病诊断与统计手册》第四版成人注意力缺陷多动障碍的描述性流行病学
Atten Defic Hyperact Disord. 2017 Mar;9(1):47-65. doi: 10.1007/s12402-016-0208-3. Epub 2016 Nov 19.
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Insomnia among current and remitted common mental disorders and the association with role functioning: results from a general population study.当前和缓解期常见精神障碍中的失眠及其与角色功能的关联:一项普通人群研究的结果
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8
ADHD and Sleep Quality: Longitudinal Analyses From Childhood to Early Adulthood in a Twin Cohort.注意缺陷多动障碍与睡眠质量:来自一个双胞胎队列的从童年到成年早期的纵向分析
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ADHD, circadian rhythms and seasonality.注意缺陷多动障碍、昼夜节律与季节性
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成人注意缺陷多动障碍患者失眠与睡眠时间的关系:一项基于一般人群的研究结果。

The Association Between Insomnia and Sleep Duration in Adults With Attention-Deficit Hyperactivity Disorder: Results From a General Population Study.

机构信息

PsyQ Expertise Center Adult ADHD, The Hague, The Netherlands.

Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands.

出版信息

J Clin Sleep Med. 2018 Mar 15;14(3):349-357. doi: 10.5664/jcsm.6976.

DOI:10.5664/jcsm.6976
PMID:29458702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5837836/
Abstract

STUDY OBJECTIVES

Insomnia and short or long sleep duration are important comorbid conditions in adults with attention-deficit hyperactivity disorder (ADHD), but reports of the association vary. In a general population study, we evaluated the relationship between ADHD symptom severity, insomnia symptoms, and sleep duration in adults.

METHODS

Data were from the third wave of the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2; n = 4,618). ADHD symptom severity and symptom dimensions (hyperactivity and inattention) were assessed using the Adult ADHD Self-Report Scale screener. Self-reported insomnia symptoms (Insomnia Rating Scale; IRS) were defined as clinically relevant if IRS ≥ 9. Self-reported short sleep duration was defined as ≤ 6 hours, and long sleep duration as ≥ 10 hours.

RESULTS

Within the group with clinically relevant ADHD symptoms, 43% reported significant insomnia symptoms (odds ratio [OR] = 2.66, 95% confidence interval [CI] 1.74-4.07); 41% short sleep duration (relative risk ratio [RRR] = 1.94, 95% CI 1.31-2.85) and 6% long sleep (RRR = 5.87, 95% CI 1.97-17.45). Increased inattention symptoms were associated with IRS ≥ 9, short and long sleep duration in fully adjusted models (OR = 1.10, 95% CI 1.06-1.14; RRR = 1.06, 95% CI 1.02-1.09; RRR = 1.16, 95% CI 1.05-1.28, respectively). Increased hyperactivity symptoms were associated with IRS ≥ 9 (OR = 1.17, 95% CI 1.11-1.23) and short sleep duration (RRR = 1.12, 95% CI 1.05-1.19).

CONCLUSIONS

Both clinically significant ADHD symptoms and inattention and hyperactivity symptom dimensions were consistently associated with insomnia symptoms and altered sleep duration. These associations confirm that sleep disturbances should be assessed and given appropriate clinical attention in adults with ADHD.

摘要

研究目的

失眠和睡眠时间短或长是成人注意力缺陷多动障碍(ADHD)的重要合并症,但相关报告存在差异。在一项普通人群研究中,我们评估了 ADHD 症状严重程度、失眠症状和成人睡眠时间之间的关系。

方法

数据来自荷兰心理健康调查和发病率研究第三波(NEMESIS-2;n=4618)。使用成人 ADHD 自我报告量表筛查器评估 ADHD 症状严重程度和症状维度(多动和注意力不集中)。如果 IRS≥9,则将自我报告的失眠症状(失眠评定量表;IRS)定义为具有临床意义。自我报告的短睡眠时间定义为≤6 小时,长睡眠时间定义为≥10 小时。

结果

在有临床意义的 ADHD 症状组中,43%的人报告有明显的失眠症状(优势比[OR] = 2.66,95%置信区间[CI] 1.74-4.07);41%的人有短睡眠时间(相对风险比[RRR] = 1.94,95%置信区间[CI] 1.31-2.85)和 6%的人有长睡眠时间(RRR = 5.87,95%置信区间[CI] 1.97-17.45)。在完全调整模型中,注意力不集中症状增加与 IRS≥9、短睡眠时间和长睡眠时间相关(OR=1.10,95%CI 1.06-1.14;RRR=1.06,95%CI 1.02-1.09;RRR=1.16,95%CI 1.05-1.28)。多动症状增加与 IRS≥9(OR=1.17,95%CI 1.11-1.23)和短睡眠时间相关(RRR=1.12,95%CI 1.05-1.19)。

结论

有临床意义的 ADHD 症状以及注意力不集中和多动症状维度均与失眠症状和睡眠时间改变一致相关。这些关联证实,在 ADHD 成人中,应评估睡眠障碍并给予适当的临床关注。