Chukanova E I, Chukanova A S
Pirogov Russian National Research Medical University, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(1):103-109. doi: 10.17116/jnevro201811811103-109.
The issues of classification, pathogenesis, pathomorphology and treatment of diabetic polyneuropathy (DPN) are addressed. Pathogenetic mechanisms of the action of alpha-lipoic acid in treatment of DPN are justified. The authors present the results of randomized placebo-controlled trials of alpha-lipoic acid that revealed the high clinical efficacy and absence of side-effects even during the long-term treatment.
探讨了糖尿病性多发性神经病（DPN）的分类、发病机制、病理形态学及治疗问题。阐明了α-硫辛酸治疗DPN的作用机制。作者介绍了α-硫辛酸随机安慰剂对照试验的结果，该试验表明即使长期治疗，α-硫辛酸仍具有高临床疗效且无副作用。
