Mirijanyan G
Yerevan State Medical University, Healthcare Management and Economics Department, Armenia.
Georgian Med News. 2018 Jan(274):88-92.
Many studies showed, that quality of life (QL ) is affected in case of gastroesophageal reflux disease (GERD). Numerous questionnaires with a wide variety of characteristics have been developed for the assessment of GERD. The current study aimed to determine the QL changes of patients with GERD. The sample consisted of 100 patients with GERD. We also formed control group, which consist of 50 practical healthy patients (without GERD). In case group we formed two subgroups- GERD with Esophagitis and GERD without Esophagitis. For QL measure we used SF-36 questionnaire. In case group 58 patients were male and 42 were female. GERD without Esophagitis subgroup included 71 cases, 41 of which were diagnosed in men and 30 in women. The mean age of this subgroup was 35.3±5.2 years. The second clinical subgroup is gastroesophageal reflux, with eosophthalic patients, which consisted of 29 cases. 17 patients in this subgroup were male and 12 female. The mean age of this subgroup was 35,4±5,3 years. The most affected subscales of patients with GERD were "Role physical functioning", "General health", "Role emotional functioning" comparing with control group according SF-36 questionnaire. In the case of GERD without an esophagus, the most affected were "Role physical functioning" and "Role emotional functioning" subscales. Regardless of the type of subgroup, QL "Bodily pain" and "General health" subscal's scores were lowIn case group patients, who have BMI>25 kg/m2 have lower scores of QL compared to the group GERD BMI<25kg/m2.
许多研究表明，胃食管反流病（GERD）患者的生活质量（QL）会受到影响。为评估GERD，已开发出众多具有各种不同特征的问卷。本研究旨在确定GERD患者的生活质量变化。样本包括100例GERD患者。我们还组建了对照组，由50名实际健康的患者（无GERD）组成。在病例组中，我们形成了两个亚组——有食管炎的GERD和无食管炎的GERD。对于生活质量测量，我们使用了SF - 36问卷。病例组中，男性患者58例，女性患者42例。无食管炎的GERD亚组包括71例，其中男性41例，女性30例。该亚组的平均年龄为35.3±5.2岁。第二个临床亚组是有食管炎的胃食管反流患者，由29例组成。该亚组中男性患者17例，女性患者12例。该亚组的平均年龄为35.4±5.3岁。根据SF - 36问卷，与对照组相比，GERD患者受影响最大的分量表是“角色身体功能”“总体健康”“角色情感功能”。在无食管炎的GERD病例中，受影响最大的是“角色身体功能”和“角色情感功能”分量表。无论亚组类型如何，生活质量“身体疼痛”和“总体健康”分量表的得分都较低。病例组中，体重指数（BMI）>25 kg/m²的患者与BMI<25 kg/m²的GERD组患者相比，生活质量得分更低。
