Zhou Ying, Guo Xiaofan, Sun Guozhe, Yu Shasha, Li Zhao, Zheng Liqiang, Sun Yingxian
a Department of Cardiology , The First Hospital of China Medical University , Shenyang , Liaoning , PR China.
b Department of Clinical Epidemiology , Library, Shengjing Hospital of China Medical University , Shenyang , Liaoning , PR China.
Gynecol Endocrinol. 2018 Aug;34(8):670-674. doi: 10.1080/09513590.2018.1441400. Epub 2018 Feb 20.
The aim of this article was to explore the link between postmenopausal status according to years since menopause (YSM) and the prevalence of metabolic syndrome (MetS). This survey was conducted from January 2012 to August 2013. A total of 6022 women (3511, 58.3% were post-menopause) from Rural Northeast China were randomly selected and examined. The prevalence of the MetS was significantly higher in postmenopausal women (Post-MW) than in premenopausal women (Pre-MW) (55.0% vs. 33.1%, p .001). The risk for MetS in Post-MW increased with the number of YSM, reaching the peak level in the 5- to 9-year group (OR, 1.55; 95% CI, 1.23-1.96), and then decreased. The 5- to 9-year group had the highest risk of high glucose (OR, 1.48; 95% CI, 1.20-1.83) and high triglycerides (adjusted OR, 1.92; 95% CI, 1.53-2.41) whereas the risk for abdominal obesity, high BP, and low HDL-C was not significantly associated with the number of YSM. These findings suggested that, in China, Post-MW with 5-9 YSMs had the highest risk of MetS. YSM can be a useful screening tool to identify women at high risk for MetS.
本文旨在探讨根据绝经年限（YSM）划分的绝经后状态与代谢综合征（MetS）患病率之间的联系。这项调查于2012年1月至2013年8月进行。从中国东北农村地区随机选取了6022名女性（3511名，58.3%为绝经后女性）并进行检查。绝经后女性（Post-MW）中MetS的患病率显著高于绝经前女性（Pre-MW）（55.0%对33.1%，p<0.001）。Post-MW中MetS的风险随YSM数量增加而增加，在5至9年组达到峰值水平（OR，1.55；95%CI，1.23 - 1.96），然后下降。5至9年组患高血糖（OR，1.48；95%CI，1.20 - 1.83）和高甘油三酯（调整后OR，1.92；95%CI，1.53 - 2.41）的风险最高，而腹部肥胖、高血压和低高密度脂蛋白胆固醇的风险与YSM数量无显著关联。这些发现表明，在中国，绝经5至9年的Post-MW患MetS的风险最高。YSM可作为识别MetS高危女性的有用筛查工具。
