Federal University of Pelotas (UFPel), Department of Preventive Veterinary, Zoonosis Control Center of UFPel, Capão do Leão, Rio Grande do Sul, Brazil.
Municipal Department of Health of Belo Horizonte, Minas Gerais, Brazil.
Epidemiol Infect. 2018 Apr;146(5):565-570. doi: 10.1017/S0950268818000109. Epub 2018 Feb 21.
The aim of this study was to evaluate the distribution of cases and the social determinants associated with death from human visceral leishmaniasis (HVL) and VL-HIV co-infection in Belo Horizonte, Minas Gerais state, Brazil, between 2006 and 2013. Descriptive statistics and analysis of associations were performed using chi-square of the raised variables, such as sex, age, skin colour and schooling of cases of HVL. During the study period, there were 866 cases of HVL with 111 deaths in Belo Horizonte. Morbidity and lethality rates (LR) of HVL in Belo Horizonte remained high over almost all the years evaluated, with an average incidence rate of 4.18 cases/100 000 inhabitants and a LR of 11.16%. With respect to skin colour, it was found that people characterised as black or mulatto had higher morbidity, followed by white. Regarding schooling, LR was more prevalent among individuals with lower education. One of the social risk factors was co-infection with HIV, which was present in many cases of HVL. Furthermore, it was found that older age and the male sex were also risk factors for death from HVL in Belo Horizonte.
本研究旨在评估巴西米纳斯吉拉斯州贝洛奥里藏特市 2006 年至 2013 年期间人类内脏利什曼病（HVL）和 HVL-HIV 合并感染病例的分布情况及与死亡相关的社会决定因素。采用卡方检验对病例的性别、年龄、肤色和受教育程度等升高变量进行描述性统计和关联分析。研究期间，贝洛奥里藏特共报告 866 例 HVL 病例，其中 111 例死亡。几乎在所有评估年份，HVL 的发病率和病死率（LR）在贝洛奥里藏特均居高不下，平均发病率为 4.18 例/10 万居民，LR 为 11.16%。就肤色而言，黑人和混血儿的发病率较高，其次是白人。就受教育程度而言，LR 在受教育程度较低的人群中更为普遍。一个社会风险因素是与 HIV 的合并感染，这在许多 HVL 病例中存在。此外，研究还发现，年龄较大和男性也是贝洛奥里藏特 HVL 死亡的风险因素。
