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肛周粉刺:一种罕见的偶然发现。

Perianal Comedones: A Rare Incidental Finding.

作者信息

Powell Priscilla R, Garza-Chapa Juana Irma, Susa Joseph S, Weis Stephen E

机构信息

Medical City Weatherford, 713 East Anderson St., Weatherford, TX 76086, USA.

Medipiel, Centro Dermatológico y Clínica Laser, Av. Vasconcelos 405 Ote., Col. Residencial San Agustín, 66260 Garza García, NL, Mexico.

出版信息

Case Rep Dermatol Med. 2017;2017:9019682. doi: 10.1155/2017/9019682. Epub 2017 Dec 31.

DOI:10.1155/2017/9019682
PMID:29464128
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5804107/
Abstract

Comedones occur when an overproliferation of keratinocytes blocks sebum secretion in a pilosebaceous duct. Comedones have multiple possible etiologies and contributing factors. While comedones are common to acne, they are also seen in occupational exposures and are associated with certain syndromes. We describe a particularly rare case of comedones at the perianus that is not associated with any known exposure or disease and is a rare incidental finding.

摘要

当角质形成细胞过度增殖阻塞皮脂腺导管中的皮脂分泌时,就会出现粉刺。粉刺有多种可能的病因和促成因素。虽然粉刺在痤疮中很常见,但在职业暴露中也可见到,并且与某些综合征有关。我们描述了一例特别罕见的肛周粉刺病例,该病例与任何已知的暴露或疾病无关,是一种罕见的偶然发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/5804107/5ea3060fb220/CRIDM2017-9019682.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/5804107/b7f34275f058/CRIDM2017-9019682.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/5804107/5ea3060fb220/CRIDM2017-9019682.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/5804107/b7f34275f058/CRIDM2017-9019682.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/5804107/5ea3060fb220/CRIDM2017-9019682.002.jpg

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Perianal comedones: a benign and rarely documented entity.肛周粉刺:一种良性且鲜有文献记载的病症。
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本文引用的文献

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Hidradenitis suppurativa and the metabolic syndrome.化脓性汗腺炎与代谢综合征
Clin Dermatol. 2018 Jan-Feb;36(1):41-47. doi: 10.1016/j.clindermatol.2017.09.007. Epub 2017 Sep 12.
2
Is sebocyte-derived leptin the missing link between hyperseborrhea, ductal hypoxia, inflammation and comedogenesis in acne vulgaris?皮脂腺细胞源性瘦素是寻常痤疮中皮脂溢出、导管缺氧、炎症和粉刺形成之间缺失的环节吗?
Exp Dermatol. 2016 Mar;25(3):181-2. doi: 10.1111/exd.12917. Epub 2016 Feb 10.
3
Strategic Targets in Acne: The Comedone Switch in Question.
痤疮的战略目标:关于粉刺转变的问题
Dermatology. 2015;231(2):105-11. doi: 10.1159/000382031. Epub 2015 Jun 23.
4
Comedonal and Cystic Fibrofolliculomas in Birt-Hogg-Dube Syndrome.Birt-Hogg-Dube综合征中的粉刺样和囊性纤维毛囊瘤
JAMA Dermatol. 2015 Jul;151(7):770-4. doi: 10.1001/jamadermatol.2015.0215.
5
Modulation of sebum oxidation and interleukin-1α levels associates with clinical improvement of mild comedonal acne.皮脂氧化和白细胞介素-1α水平的调节与轻度粉刺性痤疮的临床改善相关。
J Eur Acad Dermatol Venereol. 2014 Dec;28(12):1792-7. doi: 10.1111/jdv.12431. Epub 2014 Mar 14.
6
The sequence of inflammation, relevant biomarkers, and the pathogenesis of acne vulgaris: what does recent research show and what does it mean to the clinician?寻常痤疮的炎症过程、相关生物标志物及发病机制:近期研究有哪些发现,对临床医生有何意义?
J Drugs Dermatol. 2013 Aug;12(8 Suppl):s109-15.
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Multiple comedonelike lesions encircling the anal orifice--quiz case.围绕肛门开口的多个粉刺样损害——病例分析
Arch Dermatol. 2009 Dec;145(12):1447-52. doi: 10.1001/archdermatol.2009.289-a.
8
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Clin Colon Rectal Surg. 2004 Nov;17(4):241-5. doi: 10.1055/s-2004-836945.
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Comedogenicity in rabbit: some cosmetic ingredients/vehicles.家兔致粉刺性:某些化妆品成分/载体
Cutan Ocul Toxicol. 2007;26(4):287-92. doi: 10.1080/15569520701555383.
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Comedone formation: etiology, clinical presentation, and treatment.粉刺形成:病因、临床表现及治疗
Clin Dermatol. 2004 Sep-Oct;22(5):367-74. doi: 10.1016/j.clindermatol.2004.03.011.