对目标蛋白具有可切换亲和力的气体刺激响应性分子印迹聚合物颗粒。
Gas-stimuli-responsive molecularly imprinted polymer particles with switchable affinity for target protein.
作者信息
Kitayama Yukiya, Isomura Manabu
机构信息
Graduate School of Engineering, Kobe University, 1-1, Rokkodai-cho, Nada-ku, Kobe 657-8501, Japan.
出版信息
Chem Commun (Camb). 2018 Mar 6;54(20):2538-2541. doi: 10.1039/c7cc09889h.
PMID:29464241
Abstract
Gas-responsive molecularly imprinted polymer (MIP) particles, which have nanocavities in their shell layer for protein recognition, were developed for the first time. The MIP particles showed higher affinity for the target protein inside a CO-treated aqueous medium as compared to that under N-treated conditions, while retaining selectivity to the target protein.
摘要
首次开发出了气体响应性分子印迹聚合物（MIP）颗粒，其壳层具有用于蛋白质识别的纳米腔。与氮气处理条件下相比，MIP颗粒在一氧化碳处理的水性介质中对目标蛋白质表现出更高的亲和力，同时保持对目标蛋白质的选择性。
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