Department of Analytical Chemistry, Faculty of Chemistry, Razi University, Kermanshah, Iran.
Department of Analytical Chemistry, Faculty of Chemistry, Razi University, Kermanshah, Iran.
Mater Sci Eng C Mater Biol Appl. 2014 Mar 1;36:102-7. doi: 10.1016/j.msec.2013.11.021. Epub 2013 Nov 27.
The design and construction of a selective voltammetric sensor for propylparaben (PP) in cosmetics by using a molecularly imprinted polymer (MIP) as recognition element was introduced. The MIP was synthesized by using PP as template and methacrylic acid as functional monomer and then incorporated in the carbon paste electrode as PP sensor. The molecularly imprinted polymer-carbon paste electrode (MIP-CPE) showed very high recognition ability in comparison to non-imprinted polymer-carbon paste electrode (NIP-CPE). It was shown that electrode washing after PP extraction, led to enhanced selectivity, without noticeably decreasing the sensitivity. Some parameters affecting sensor response were optimized, and a calibration curve was then plotted using differential pulse voltammetric (DPV) technique. A dynamic linear range of 1 nM to 100 nM was obtained. The detection limit of the sensor was calculated to be equal to 0.32 nM. The imprinted electrode also displayed good selectivity for PP and selectivity coefficients were 2.29 and 1.66 for methylparaben (MP) and ethylparaben (EP) respectively. Structural analogs, such as phenol and p-hydroxybenzoic acid had almost no response. This sensor was used successfully for propylparaben determination in cosmetic sample.
采用分子印迹聚合物(MIP)作为识别元件,设计并构建了一种用于化妆品中对羟基苯甲酸丙酯(PP)的选择性伏安传感器。该 MIP 以 PP 为模板,甲基丙烯酸为功能单体合成,然后作为 PP 传感器掺入到碳糊电极中。与非印迹聚合物-碳糊电极(NIP-CPE)相比,分子印迹聚合物-碳糊电极(MIP-CPE)具有非常高的识别能力。结果表明,在 PP 提取后进行电极清洗,可提高选择性,而不会明显降低灵敏度。优化了影响传感器响应的一些参数,然后使用差分脉冲伏安法(DPV)技术绘制校准曲线。得到了 1 nM 至 100 nM 的动态线性范围。传感器的检测限计算为 0.32 nM。印迹电极对 PP 也表现出良好的选择性,对甲基对羟基苯甲酸酯(MP)和乙基对羟基苯甲酸酯(EP)的选择性系数分别为 2.29 和 1.66。结构类似物,如苯酚和对羟基苯甲酸几乎没有响应。该传感器成功用于化妆品样品中对羟基苯甲酸丙酯的测定。
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