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罕见及不常见肝脏病变中发生的恶性转化:导管板畸形的纤维多囊疾病形式及胆管腺纤维瘤

Malignant Transformation Arising Within Unusual and Rare Hepatic Lesions: Fibropolycystic Disease Form of Ductal Plate Malformation and Biliary Adenofibroma.

作者信息

Chua Darren, Chiow Adrian Kah Heng, Ang Tiing Leong, Wang Lai Mun

机构信息

1 Changi General Hospital SingHealth, Singapore, Singapore.

2 Ludwig Institute, University of Oxford Nuffield Department of Medicine, Oxford, England.

出版信息

Int J Surg Pathol. 2018 Sep;26(6):542-550. doi: 10.1177/1066896918758172. Epub 2018 Feb 21.

DOI:10.1177/1066896918758172
PMID:29464972
Abstract

Cholangiocarcinoma is the second most common hepatobiliary cancer following hepatocellular carcinoma, and 20% to 25% are intrahepatic. We describe 2 cases of intrahepatic cholangiocarcinoma arising within unusual and rare hepatic lesions, fibropolycystic liver disease form of ductal plate malformation and biliary adenofibroma, whose association with malignancy is rarely reported in the literature.

摘要

胆管癌是继肝细胞癌之后第二常见的肝胆系统癌症,其中20%至25%为肝内胆管癌。我们描述了2例发生于不寻常且罕见肝脏病变(导管板畸形的纤维多囊肝疾病形式和胆管腺纤维瘤)的肝内胆管癌病例,其与恶性肿瘤的关联在文献中鲜有报道。

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Hepatic Biliary Adenofibroma: Histological Characteristics, Diagnostic Challenges, and Its Role as a Precursor to Intrahepatic Cholangiocarcinoma.肝内胆管腺纤维瘤:组织学特征、诊断挑战及其作为肝内胆管癌前体的作用
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