Wójcik Dorota, Krzewska Aleksandra, Szalewski Leszek, Pietryka-Michałowska Elżbieta, Szalewska Magdalena, Krzewski Szymon, Pels Elżbieta, Beń-Skowronek Iwona
Chair and Department of Paedodontics, Medical University of Lublin, Poland Department of Paediatric Endocrinology and Diabetology with Endocrine- Metabolic Laboratory, Medical University of Lublin Department of Dental Prosthetics Department of Mathematics and Medical Biostatistics Student Research Group at the Department of Dental Prosthetics Medical University of Lublin, Poland.
Medicine (Baltimore). 2018 Feb;97(8):e9811. doi: 10.1097/MD.0000000000009811.
Vitamin D may prevent dental caries. To date, no attempts have been made to examine the correlation between the incidence of caries and the concentrations of vitamin D in children with pituitary growth hormone deficiency.The study observed patients of the Department of Endocrinology and Diabetology of the University Paediatric Hospital of the Medical University of Lublin treated with human recombinant growth hormone for pituitary growth hormone deficiency (GHD). The study was conducted between October 2014 and June 2015. The study group consisted of 121 children and adolescents (6-17 years old), including 56 children from rural areas and 65 children from urban areas. The study group was stratified by area of residence.In our study, the increase in vitamin D3 [25(OH)D] levels reduced the D component by 0.66 per each 10 ng/mL of vitamin D3 concentration. The percentage of children with active caries in rural areas is 91.07% (n = 51), which is significantly higher than the percentage of children with active caries in urban areas (81.54%, n = 53).To date, information regarding the potential possibility of reducing the incidence of dental caries by means of increasing the levels of vitamin D was sidelined by paediatricians and dentists alike. Therefore, this aspect of caries prevention should be highlighted.
维生素D可能预防龋齿。迄今为止，尚未有人尝试研究垂体生长激素缺乏症患儿的龋齿发病率与维生素D浓度之间的相关性。该研究观察了卢布林医科大学大学儿童医院内分泌与糖尿病科中接受重组人生长激素治疗垂体生长激素缺乏症（GHD）的患者。研究于2014年10月至2015年6月进行。研究组由121名儿童和青少年（6 - 17岁）组成，其中包括56名农村儿童和65名城市儿童。研究组按居住地区分层。在我们的研究中，维生素D3[25(OH)D]水平每增加10 ng/mL，D成分就降低0.66。农村地区患活动性龋齿的儿童比例为91.07%（n = 51），显著高于城市地区患活动性龋齿的儿童比例（81.54%，n = 53）。迄今为止，儿科医生和牙医都忽视了关于通过提高维生素D水平来降低龋齿发病率的潜在可能性的信息。因此，应强调龋齿预防的这一方面。
