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贝类黏液在传播广州管圆线虫(一种潜在严重的神经系统感染)中的作用。

Role of Gastropod Mucus in the Transmission of Angiostrongylus cantonensis, a Potentially Serious Neurological Infection.

机构信息

Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A Burns School of Medicine , University of Hawaii at Manoa , Honolulu , Hawaii 96813 , United States.

出版信息

ACS Chem Neurosci. 2018 Apr 18;9(4):629-632. doi: 10.1021/acschemneuro.7b00491. Epub 2018 Mar 6.

DOI:10.1021/acschemneuro.7b00491
PMID:29465976
Abstract

Angiostrongylus cantonensis, the rat lungworm, is endemic to Hawaii. A recent increase in the number of cases has drawn intense local and national media attention. As a result there is an increased fear of acquiring the disease from local produce, which has the potential to adversely affect the income of local farmers. The most common means of transmission is by the ingestion of an infected intermediate host. Other modes of transmission have been suggested including infectious larvae being released into the mucus trail of gastropods. This literature review indicates that mucus trails from infected gastropods poses a minimal risk to humans.

摘要

广东住血线虫,即鼠肺虫,是夏威夷的地方病。近期病例数量的增加引起了当地和全国媒体的强烈关注。因此,人们越来越担心从当地农产品中感染这种疾病,这有可能对当地农民的收入产生不利影响。最常见的传播途径是摄入受感染的中间宿主。其他传播方式也有被提出,包括感染的幼虫被释放到腹足类动物的黏液轨迹中。这篇文献综述表明,受感染的腹足类动物的黏液轨迹对人类的风险很小。

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ACS Chem Neurosci. 2018 Apr 18;9(4):629-632. doi: 10.1021/acschemneuro.7b00491. Epub 2018 Mar 6.
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引用本文的文献

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One Health. 2023 Nov 27;17:100658. doi: 10.1016/j.onehlt.2023.100658. eCollection 2023 Dec.
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Update on the First Finding of the Rat Lungworm, in spp. in Continental Europe, Valencia, Spain, 2022.2022年西班牙巴伦西亚大陆地区首次发现福寿螺体内的广州管圆线虫的最新情况
Pathogens. 2023 Apr 6;12(4):567. doi: 10.3390/pathogens12040567.
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Neuroangiostrongyliasis: Global Spread of an Emerging Tropical Disease.神经血管圆线虫病:一种新兴热带病的全球传播。
Am J Trop Med Hyg. 2022 Nov 7;107(6):1166-1172. doi: 10.4269/ajtmh.22-0360. Print 2022 Dec 14.
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Synaptic loss and progression in mice infected with Angiostrongylus cantonensis in the early stage.感染广东血管圆线虫的小鼠早期的突触丧失和进展。
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