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文献综述强调缺乏儿科捐赠协议,但确定了可能指导其制定的共同主题。

Literature overview highlights lack of paediatric donation protocols but identifies common themes that could guide their development.

机构信息

Department of Pediatrics, Beatrix Children's Hospital, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.

University Medical Centre Groningen Transplant Centre, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.

出版信息

Acta Paediatr. 2018 May;107(5):744-752. doi: 10.1111/apa.14288. Epub 2018 Mar 22.

Abstract

AIM

Paediatric donation is a unique and extremely sensitive process that requires specific knowledge and competencies. Most countries use protocols for organ and tissue donation to ensure optimal care for the donor and family, but these mainly focus on adults. However, the donation process for children differs from adults in many ways. An overview of the literature was performed to identify protocols for the paediatric population.

METHODS

PubMed, Web of Science, EMBASE and the Internet were searched up to March 2016 for papers or other sources in English related to specific organ and tissue donation protocols for children and neonates. This comprised title, abstract and then full-text screening of relevant data.

RESULTS

We included 12 papers and two electronic sources that were mainly from North America and Europe. Most discussed donations after cardiac death. The recurring themes included identifying potential donors, approaching parents, palliative care and collaboration with organ procurement organisations. Most papers called for paediatric donation policies to be standardised.

CONCLUSION

Scientific publications in English on paediatric donation protocols are very scarce. No comprehensive paediatric donation protocol was found. We identified several recurring themes in the literature that could be used to develop such protocols.

摘要

目的

儿科捐赠是一个独特且极其敏感的过程,需要特定的知识和能力。大多数国家都使用器官和组织捐赠协议来确保捐赠者和家属得到最佳的护理,但这些协议主要针对成年人。然而,儿童的捐赠过程在许多方面与成年人不同。本文对文献进行了综述,以确定针对儿科人群的协议。

方法

截至 2016 年 3 月,我们在 PubMed、Web of Science、EMBASE 和互联网上检索了英文的与儿童和新生儿特定器官和组织捐赠协议相关的论文或其他来源,包括标题、摘要和全文筛选相关数据。

结果

我们纳入了 12 篇论文和 2 个电子资源,主要来自北美和欧洲。大多数文章讨论了心脏死亡后的捐赠。反复出现的主题包括确定潜在的捐赠者、与家长联系、姑息治疗以及与器官获取组织的合作。大多数文章呼吁制定标准化的儿科捐赠政策。

结论

英文的儿科捐赠协议的科学出版物非常稀缺。我们没有发现全面的儿科捐赠协议。我们在文献中确定了一些反复出现的主题,可以用来制定这样的协议。

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本文引用的文献

1
Pediatric Donation After Circulatory Determination of Death: A Scoping Review.
Pediatr Crit Care Med. 2016 Mar;17(3):e87-e108. doi: 10.1097/PCC.0000000000000602.
2
Neonatal and Pediatric Organ Donation: Ethical Perspectives and Implications for Policy.
Front Pediatr. 2015 Nov 17;3:100. doi: 10.3389/fped.2015.00100. eCollection 2015.
3
Pediatric Deceased Donation-A Report of the Transplantation Society Meeting in Geneva.
Transplantation. 2015 Jul;99(7):1403-9. doi: 10.1097/TP.0000000000000758.
4
Children as donors: a national study to assess procurement of organs and tissues in pediatric intensive care units.
Transpl Int. 2012 Dec;25(12):1268-74. doi: 10.1111/j.1432-2277.2012.01567.x. Epub 2012 Oct 11.
6
Key factors in paediatric organ and tissue donation: an overview of literature in a chronological working model.
Transpl Int. 2012 Mar;25(3):265-71. doi: 10.1111/j.1432-2277.2011.01407.x. Epub 2011 Dec 27.
7
Children's opinions about organ donation: a first step to assent?
Eur J Public Health. 2012 Aug;22(4):529-33. doi: 10.1093/eurpub/ckr088. Epub 2011 Jul 12.
8
PICU staff attitude towards organ donor identification and donation after circulatory death.
Arch Dis Child. 2011 Jul;96(7):700. doi: 10.1136/adc.2011.210609. Epub 2011 Feb 9.
9
Identifying potential heart donors among newborns undergoing circulatory determination of death.
J Heart Lung Transplant. 2011 Apr;30(4):389-94. doi: 10.1016/j.healun.2010.09.016. Epub 2010 Dec 24.
10
Policy statement--pediatric organ donation and transplantation.
Pediatrics. 2010 Apr;125(4):822-8. doi: 10.1542/peds.2010-0081. Epub 2010 Mar 29.

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