University of Delaware, Newark.
Northwestern University, Chicago, Illinois.
Arthritis Care Res (Hoboken). 2018 Oct;70(10):1448-1454. doi: 10.1002/acr.23511.
To compare objectively measured physical activity in older adults with symptomatic knee osteoarthritis (OA) with similarly aged adults without osteoarthritis (OA) or knee symptoms from the general population.
We included people ages 50-85 years with symptomatic knee OA from the Osteoarthritis Initiative (OAI, n = 491), and ages 50-85 years from the general population using National Health and Nutrition Examination Survey (NHANES, n = 449) data. A uniaxial accelerometer was worn for ≥10 hours/day for ≥4 days in the NHANES group in 2003-2004 and in the OAI group in 2008-2010. We calculated time spent in moderate-to-vigorous physical activity (MVPA in minutes/day) and described differences in MVPA and demographic variables between the samples. We conducted matched-pairs sensitivity analyses to further evaluate the role of potential confounders.
Both cohorts had similarly low levels of physical activity in age- and sex-specific strata. Time in MVPA ranged from a median of 1-22 minutes/day in people with symptomatic knee OA, and from 1-24 minutes/day in the general population without OA or knee pain. These results were similar in sensitivity analyses.
Time spent in MVPA was similarly low in those with symptomatic knee OA as in older adults without knee pain or OA.
比较有症状的膝骨关节炎(OA)老年患者与一般人群中无 OA 或膝关节症状的同龄患者的客观测量的体力活动。
我们纳入了来自骨关节炎倡议(OAI)的有症状膝 OA 患者(年龄 50-85 岁,n=491)和来自全国健康和营养检查调查(NHANES)的一般人群(年龄 50-85 岁,n=449)。在 NHANES 组中,2003-2004 年期间使用单轴加速度计佩戴≥10 小时/天,≥4 天;在 OAI 组中,2008-2010 年期间使用单轴加速度计佩戴≥10 小时/天,≥4 天。我们计算了中等到剧烈体力活动(MVPA,以分钟/天计)的时间,并描述了两个样本中 MVPA 和人口统计学变量的差异。我们进行了匹配对敏感性分析,以进一步评估潜在混杂因素的作用。
两个队列在年龄和性别特定分层中都具有相似的低水平体力活动。在有症状的膝 OA 患者中,MVPA 的时间中位数为 1-22 分钟/天,在无 OA 或膝关节疼痛的一般人群中为 1-24 分钟/天。这些结果在敏感性分析中也相似。
有症状的膝 OA 患者的 MVPA 时间与无膝关节疼痛或 OA 的老年患者相似。