非甾体类抗炎药肝毒性的最新进展。
Recent Advances in Hepatotoxicity of Non Steroidal Anti-Inflammatory Drugs.
机构信息
Montpellier School of Medicine Liver and Transplantation Unit.
出版信息
Ann Hepatol. 2018 Mar 1;17(2):187-191. doi: 10.5604/01.3001.0010.8633.
PMID:29469052
Abstract
Non-steroidal-anti-inflammatory drugs (NSAIDs) make a heterogenous pharmaco-therapeutic class of drugs among the most used drugs worldwide with various indications, modes of administration and increasing automedication. NSAIDs can cause acute liver injury with variable severity. The recent identification of genetic markers might facilitate the diagnosis and the prediction of hepatotoxicity risk.
摘要
非甾体抗炎药（NSAIDs）是世界范围内使用最广泛的药物之一，因其具有多种适应证、给药方式和日益增加的自我用药特点，成为一个异质性的药物治疗类别。NSAIDs 可引起急性肝损伤，其严重程度不一。最近发现的遗传标志物可能有助于诊断和预测肝毒性风险。
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