Di Xia Fan, Ly Amy, Smith Gideon P
Harvard Medical School, Boston, Massachusetts.
Dermatol Online J. 2017 Jul 15;23(7):13030/qt51g1k0zm.
Idiopathic granulomatous mastitis (IGM) is a benign chronic inflammatory breast disease of unknown etiology. No consensus exists as to the best therapeutic approach, though treatment choices include antibiotics, drainage, surgical excision, steroids, methotrexate, and observation. Herein we report a case of idiopathic granulomatous mastitis that was refractory to methotrexate and intralesional and systemic steroids but responded well to mycophenolate mofetil 1500mg twice daily. To our knowledge, this is the first report of the effective use of mycophenolate mofetil in idiopathic granulomatous mastitis.
特发性肉芽肿性乳腺炎（IGM）是一种病因不明的良性慢性炎症性乳腺疾病。尽管治疗选择包括抗生素、引流、手术切除、类固醇、甲氨蝶呤和观察，但对于最佳治疗方法尚无共识。在此，我们报告一例特发性肉芽肿性乳腺炎病例，该病例对甲氨蝶呤、病灶内及全身性类固醇治疗无效，但对霉酚酸酯每日两次、每次1500mg治疗反应良好。据我们所知，这是霉酚酸酯有效用于特发性肉芽肿性乳腺炎的首例报告。
