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以坏死性面部肿块为表现的播散性皮肤孢子丝菌病:病例报告及文献复习

Disseminated cutaneous sporotrichosis presenting as a necrotic facial mass: Case and review.

作者信息

He Yong, Ma Chelsea, Fung Maxwell, Fitzmaurice Sarah

机构信息

Department of Dermatology, University of California Davis Health System, Sacramento, California.

出版信息

Dermatol Online J. 2017 Jul 15;23(7):13030/qt5zd47238.

Abstract

Sporotrichosis is a subcutaneous mycotic infection caused by Sporothrix schenckii, a group of common saprophytes of soil, plants, and organic debris. Disseminated forms may be seen in the setting of immunosuppression and are typically treated initially with intravenous lipidized amphotericin B. We report an unusual case of a 65-year-old woman who developed disseminated cutaneous sporotrichosis with extensive facial involvement in the absence of a known primary inoculation. Her cutaneous lesions completely resolved after treatment with intravenous posaconazole without amphotericin B.

摘要

孢子丝菌病是由申克孢子丝菌引起的一种皮下真菌感染,申克孢子丝菌是土壤、植物和有机碎屑中一组常见的腐生菌。播散型孢子丝菌病可见于免疫抑制的情况下,通常最初采用静脉注射脂质体两性霉素B进行治疗。我们报告了一例罕见病例,一名65岁女性在无已知原发性接种的情况下发生了播散性皮肤孢子丝菌病,面部广泛受累。在接受静脉注射泊沙康唑而非两性霉素B治疗后,她的皮肤病变完全消退。

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