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环状弹性组织溶解性巨细胞肉芽肿:一种“直观”的诊断。

Annular elastolytic giant cell granuloma: a "visible" diagnosis.

作者信息

Raposo Inês, Mota Fernando, Lobo Inês, Brandão José Ricardo, Selores Manuela

机构信息

Department of Dermatology, Centro Hospitalar do Porto, Portugal.

出版信息

Dermatol Online J. 2017 Jul 15;23(7):13030/qt9rq3j927.

Abstract

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of undetermined cause, characterized by annular plaques with raised erythematous borders in sun-exposed skin. The typical histologic features are dermal infiltration by multinucleated giant cells, elastin degeneration, and elastophagocytosis. The authors describe a clinical case of AEGCG, which exhibited an excellent response to hydroxycloroquine.

摘要

环状弹性组织溶解性巨细胞肉芽肿(AEGCG)是一种病因不明的罕见肉芽肿性皮肤病,其特征为在暴露于阳光的皮肤出现边界呈红斑状隆起的环状斑块。典型的组织学特征是多核巨细胞浸润真皮、弹性蛋白变性和弹性蛋白吞噬。作者描述了一例AEGCG临床病例,该病例对羟氯喹表现出良好反应。

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