Takala T E, Vuori J, Anttinen H, Väänänen K, Myllylä R
Pflugers Arch. 1986 Nov;407(5):500-3. doi: 10.1007/BF00657507.
The effect of prolonged heavy physical exercise on serum galactosylhydroxylysyl glucosyltransferase activity (S-GGT) and serum type III procollagen aminoterminal propeptide (S-Pro(III)-N-P) concentration was studied in healthy male long-distance runners. S-GGT increased gradually by about 70% (p less than 0.01) during a competitive 24-h run, and a rising trend was also observed in S-Pro(III)-N-P. After the termination of the run S-GGT was normalized in two days, but the increase in S-Pro(III)-N-P continued up to one day after the race, reaching nearly 40% (p less than 0.005). The alterations in S-GGT and S-Pro(III)-N-P showed no significant correlation with S-CK, S-LDH or the distance run. The most likely explanation for the increases in S-GGT and S-Pro(III)-N-P is that prolonged heavy exercise injures the collagen-synthesizing cells of the connective tissue, leading to a short-term increase in type III procollagen production.
在健康男性长跑运动员中，研究了长时间剧烈体育锻炼对血清半乳糖基羟赖氨酰葡糖基转移酶活性（S-GGT）和血清III型前胶原氨基端前肽（S-Pro(III)-N-P）浓度的影响。在一场持续24小时的比赛中，S-GGT逐渐增加约70%（p<0.01），并且在S-Pro(III)-N-P中也观察到上升趋势。比赛结束后，S-GGT在两天内恢复正常，但S-Pro(III)-N-P的增加一直持续到赛后一天，达到近40%（p<0.005）。S-GGT和S-Pro(III)-N-P的变化与S-CK、S-LDH或跑步距离均无显著相关性。S-GGT和S-Pro(III)-N-P增加的最可能解释是，长时间剧烈运动损伤了结缔组织的胶原合成细胞，导致III型前胶原产量短期增加。
