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韩国人骨关节炎与睡眠时长的关联:一项全国性横断面观察性研究。

The association between osteoarthritis and sleep duration in Koreans: a nationwide cross-sectional observational study.

机构信息

Korea University College of Medicine, Seoul, South Korea.

Department of Rheumatology, Korea University Guro Hospital, Seoul, South Korea.

出版信息

Clin Rheumatol. 2018 Jun;37(6):1653-1659. doi: 10.1007/s10067-018-4040-3. Epub 2018 Feb 22.

DOI:10.1007/s10067-018-4040-3
PMID:29470739
Abstract

Osteoarthritis (OA) causes chronic pain, physical disability, and mental health deterioration and reduces the quality of life of patients. Sleep is an important factor in the recovery, and adequate sleep is important for quality of life. Several features of patients with OA can affect sleep time, and sleep also affects OA. We investigated the relationship between OA and sleep duration. Data for 2010-2012 were collected from the Korea National Health and Nutrition Examination Survey. We included 11,540 participants (4915 men and 6625 women). Patients with OA were defined as participants with knee/hip joint pain and radiographic changes of the knee/hip joints. Sleep time was divided into 4 sections as follows: (1) 0-3 h, (2) 4-5 h, (3) 6-7 h, and (4) ≥ 8 h. Sleep time of 6 and 7 h was the most frequent and set as the reference time. In the multiple logistic regression model, the patients who slept for 0-3 and 4-5 h had odds ratios (ORs) of 2.28 (95% confidence interval [CI] 1.14-4.55) and 1.38 (95% CI 1.01-1.89) for men and 1.63 (95% CI 1.19-2.24) and 1.26 (95% CI 1.08-1.47) for women, respectively, for having OA. The prevalence of OA was lowest in the participants who had 6-7 h of sleep and progressively increased with shorter sleep time. Thus, sleep duration was significantly associated with OA.

摘要

骨关节炎(OA)会导致慢性疼痛、身体残疾和心理健康恶化,降低患者的生活质量。睡眠是康复的重要因素,充足的睡眠对生活质量很重要。OA 患者的几个特征会影响睡眠时间,而睡眠也会影响 OA。我们研究了 OA 和睡眠时间之间的关系。数据来自 2010-2012 年的韩国国家健康和营养检查调查。我们纳入了 11540 名参与者(4915 名男性和 6625 名女性)。OA 患者被定义为膝关节/髋关节疼痛且膝关节/髋关节有放射影像学改变的参与者。睡眠时间分为 4 个部分:(1)0-3 小时,(2)4-5 小时,(3)6-7 小时,(4)≥8 小时。6 小时和 7 小时的睡眠时间最常见,被设为参考时间。在多因素逻辑回归模型中,睡眠时间为 0-3 小时和 4-5 小时的男性和女性发生 OA 的比值比(OR)分别为 2.28(95%可信区间[CI]:1.14-4.55)和 1.38(95% CI:1.01-1.89)和 1.63(95% CI:1.19-2.24)和 1.26(95% CI:1.08-1.47)。睡眠时间为 6-7 小时的参与者中 OA 的患病率最低,随着睡眠时间缩短而逐渐升高。因此,睡眠时间与 OA 显著相关。

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