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[银杏叶提取物治疗下肢动脉病。一项为期65周的试验]

[Ginkgo biloba extract in the treatment of arteriopathy of the lower extremities. A 65-week trial].

作者信息

Bauer U

出版信息

Presse Med. 1986 Sep 25;15(31):1546-9.

PMID:2947095
Abstract

Thirty-six patients with arteritis were treated with Ginkgo biloba extract for sixty-five weeks. For the first six months of the treatment period, these patients participated in a double-blind randomised comparison with 35 well matched patients taking placebo. Subsequently, those patients taking Ginkgo biloba extract were given the option to continue treatment on an open basis with follow-up at regular three-monthly intervals. Ginkgo biloba extract therapy gave significantly greater pain relief and walking tolerance than the placebo after 6 months of treatment, and this improvement continued throughout the whole duration of the study. This symptomatic and measurable improvement was combined with excellent tolerance of the drug.

摘要

36例动脉炎患者接受银杏叶提取物治疗65周。在治疗期的前6个月,这些患者与35例匹配良好的服用安慰剂的患者进行了双盲随机对照试验。随后,那些服用银杏叶提取物的患者可以选择在开放的基础上继续治疗,并每三个月定期随访。治疗6个月后,银杏叶提取物治疗组的疼痛缓解和行走耐力明显优于安慰剂组,并且这种改善在整个研究期间持续存在。这种症状性和可测量的改善与药物的良好耐受性相结合。

相似文献

1
[Ginkgo biloba extract in the treatment of arteriopathy of the lower extremities. A 65-week trial].[银杏叶提取物治疗下肢动脉病。一项为期65周的试验]
Presse Med. 1986 Sep 25;15(31):1546-9.
2
6-Month double-blind randomised clinical trial of Ginkgo biloba extract versus placebo in two parallel groups in patients suffering from peripheral arterial insufficiency.银杏叶提取物与安慰剂针对外周动脉供血不足患者进行的双盲随机临床试验,两组平行对照,为期6个月。
Arzneimittelforschung. 1984;34(6):716-20.
3
Comparison of two dosages of ginkgo biloba extract EGb 761 in patients with peripheral arterial occlusive disease Fontaine's stage IIb. A randomised, double-blind, multicentric clinical trial.两种剂量银杏叶提取物EGb 761用于外周动脉闭塞性疾病Fontaine IIb期患者的比较:一项随机、双盲、多中心临床试验。
Arzneimittelforschung. 1999 Nov;49(11):900-4. doi: 10.1055/s-0031-1300524.
4
[Treatment of equilibrium disorders with Ginkgo biloba extract. A multicenter double-blind drug vs. placebo study].[银杏叶提取物治疗平衡障碍。一项多中心双盲药物与安慰剂对照研究]
Presse Med. 1986 Sep 25;15(31):1569-72.
5
[Multicenter randomized double-blind drug vs. placebo study of the treatment of tinnitus with Ginkgo biloba extract].
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[Placebo-controlled double-blind study of the effectiveness of Ginkgo biloba special extract EGb 761 in trained patients with intermittent claudication].银杏叶特殊提取物EGb 761对间歇性跛行训练患者有效性的安慰剂对照双盲研究
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[Treatment of senile macular degeneration with Ginkgo biloba extract. A preliminary double-blind drug vs. placebo study].[银杏叶提取物治疗老年性黄斑变性。一项初步的双盲药物与安慰剂对照研究]
Presse Med. 1986 Sep 25;15(31):1556-8.
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Presse Med. 1986 Sep 25;15(31):1583-7.
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[Efficacy of an extract of Ginkgo biloba in the treatment of chronic obliterating arteriopathies of the lower limbs in stage III of Fontaine's classification].[银杏叶提取物治疗Fontaine分期III期下肢慢性闭塞性动脉病的疗效]
J Mal Vasc. 1989;14(3):177-82.
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[Effect of Ginkgo biloba extract in arterial occlusive disease. Randomized placebo controlled crossover study].
Fortschr Med. 1987 Jul 10;105(20):397-400.

引用本文的文献

1
Ginkgo biloba for intermittent claudication.银杏叶治疗间歇性跛行。
Cochrane Database Syst Rev. 2013 Jun 6;2013(6):CD006888. doi: 10.1002/14651858.CD006888.pub3.