Lagrue G, Behar A, Kazandjian M, Rahbar K
Presse Med. 1986 Sep 25;15(31):1550-3.
Idiopathic cyclic oedema is a frequent and often unrecognized condition in young women. It is characterized by water and sodium retention with secondary hyperaldosteronism due to capillary hyperpermeability. Treatment is not easy. It includes spironolactone, sometimes sympathomimetics and hygienic-dietetic measures. Thiazide diuretics and laxatives must be avoided. Correcting the capillary defect is of paramount importance. This defect is detected and measured by Landis' labelled albumin test. The authors have tried Ginkgo biloba extract administered either orally or by intravenous infusion. Full correction of the biological anomaly was obtained in 10 cases in which Landis' test was performed before and after oral treatment, and in the 5 cases treated by intravenous infusion.
特发性周期性水肿在年轻女性中很常见，且常常未被认识。其特征是由于毛细血管通透性增加导致水和钠潴留以及继发性醛固酮增多症。治疗并不容易。治疗方法包括使用螺内酯，有时还会使用拟交感神经药以及卫生饮食措施。必须避免使用噻嗪类利尿剂和泻药。纠正毛细血管缺陷至关重要。这种缺陷通过兰迪斯标记白蛋白试验来检测和测量。作者尝试了口服或静脉输注银杏叶提取物。在10例口服治疗前后进行兰迪斯试验的病例以及5例静脉输注治疗的病例中，生物学异常均得到了完全纠正。
