Nano-Science Center & Department of Chemistry , University of Copenhagen , Universitetsparken 5 , 2100 Copenhagen Ø, Denmark.
FRS-systems ApS , Hovedgaden 20 , 4621 Gadstrup , Denmark.
ACS Sens. 2018 Mar 23;3(3):692-699. doi: 10.1021/acssensors.8b00024. Epub 2018 Mar 1.
A new four-component organically modified silicate (ORMOSIL) material was developed with optical pH sensors in mind. Through a sol-gel process, the porosity of an ORMOSIL framework was optimized to allow rapid diffusion of protons, ideal for fast response to pH in an optical sensor. The optically transparent material was produced by catalyzing the dual polymerization of 3-(glycidoxy)propyltrimethoxysilane (GPTMS) and propyltriethoxysilane (PrTES) with boron trifluoride diethyl etherate. The performance of the resulting material in fluorescence based optical pH sensors was evaluated by incorporation of active dye components in the inorganic polymer framework. It is demonstrated that the material has a short response time ( t < 30 s) and high stability in medium and during storage, and resulting sensor spots are biocompatible. It is concluded that this ORMOSIL material has excellent properties for optical pH sensors.
一种新型的四组分有机改性硅酸盐（ORMOSIL）材料是为光学 pH 传感器而开发的。通过溶胶-凝胶工艺，优化了 ORMOSIL 骨架的多孔性，以允许质子快速扩散，非常适合光学传感器中对 pH 的快速响应。通过催化 3-(缩水甘油氧基)丙基三甲氧基硅烷（GPTMS）和丙基三乙氧基硅烷（PrTES）与硼酸三氟二乙醚的双重聚合反应，生成了光学透明材料。通过在无机聚合物骨架中掺入活性染料成分，评估了所得材料在荧光基光学 pH 传感器中的性能。结果表明，该材料具有短的响应时间（t<30 s）和在介质中和储存期间的高稳定性，并且得到的传感器斑点是生物相容的。结论是，这种 ORMOSIL 材料具有光学 pH 传感器的优异性能。
