Department of Physics, Faculty of Engineering and Physical Science, University of Surrey, Guildford, UK; Department of Medical Physics, Portsmouth Hospitals NHS Trust, Portsmouth, UK.
Department of Physics, Faculty of Engineering and Physical Science, University of Surrey, Guildford, UK; Department of Medical Physics, Portsmouth Hospitals NHS Trust, Portsmouth, UK.
Phys Med. 2018 Jan;45:59-64. doi: 10.1016/j.ejmp.2017.11.036. Epub 2017 Dec 19.
To define a method and investigate how the adjustment of scan parameters affected the image quality and Hounsfield units (HUs) on a CT scanner used for radiotherapy treatment planning. A lack of similar investigations in the literature may be a contributing factor in the apparent reluctance to optimise radiotherapy CT protocols.
A Catphan phantom was used to assess how image quality on a Toshiba Aquilion LB scanner changed with scan parameters. Acquisition and reconstruction field-of-view (FOV), collimation, image slice thickness, effective mAs per rotation and reconstruction algorithm were varied. Changes were assessed for HUs of different materials, high contrast spatial resolution (HCSR), contrast-noise ratio (CNR), HU uniformity, scan direction low contrast and CT dose-index.
CNR and HCSR varied most with reconstruction algorithm, reconstruction FOV and effective mAs. Collimation, but not image slice width, had a significant effect on CT dose-index with narrower collimation giving higher doses. Dose increased with effective mAs. Highest HU differences were seen when changing reconstruction algorithm: 56 HU for densities close to water and 117 HU for bone-like materials. Acquisition FOV affected the HUs but reconstruction FOV and effective mAs did not.
All the scan parameters investigated affected the image quality metrics. Reconstruction algorithm, reconstruction FOV, collimation and effective mAs were most important. Reconstruction algorithm and acquisition FOV had significant effect on HU. The methodology is applicable to radiotherapy CT scanners when investigating image quality optimisation, prior to assessing the impact of scan protocol changes on clinical CT images and treatment plans.
定义一种方法,并研究调整扫描参数如何影响用于放射治疗计划的 CT 扫描仪的图像质量和亨氏单位 (HU)。文献中缺乏类似的研究可能是人们不愿意优化放射治疗 CT 方案的一个因素。
使用东芝 Aquilion LB 扫描仪上的 Catphan 体模来评估图像质量随扫描参数的变化情况。改变采集和重建视野 (FOV)、准直、图像切片厚度、每旋转有效毫安数和重建算法。评估不同材料的 HU、高对比度空间分辨率 (HCSR)、对比噪声比 (CNR)、HU 均匀性、扫描方向低对比度和 CT 剂量指数的变化。
CNR 和 HCSR 随重建算法、重建 FOV 和有效毫安数变化最大。准直而非图像切片宽度对 CT 剂量指数有显著影响,较窄的准直会产生更高的剂量。剂量随有效毫安数增加而增加。在改变重建算法时,HU 差异最大:接近水的密度为 56 HU,类似骨的材料为 117 HU。采集 FOV 会影响 HU,但重建 FOV 和有效毫安数不会。
所有研究的扫描参数都影响图像质量指标。重建算法、重建 FOV、准直和有效毫安数最为重要。重建算法和采集 FOV 对 HU 有显著影响。该方法适用于放射治疗 CT 扫描仪,用于在评估扫描协议变化对临床 CT 图像和治疗计划的影响之前,研究图像质量优化。