Boutté P, Deville A, Barthélémy D, Bérard E, Muller J M, Mariani R
Presse Med. 1986 Nov 8;15(39):1965-6.
Female homozygous twins presented with alloimmune neonatal neutropenia due to a maternal neutrophil-specific anti-NA2 antibody. The disease is usually benign, but when accompanied by severe infection it may require exchange transfusion and transfusion of granulocytes free of the antigen involved in the immunological conflict. Owing to the risk of relapse in subsequent pregnancies, the haemogram of the following infants must be supervised.
一对女性同卵双胞胎因母亲的中性粒细胞特异性抗NA2抗体而出现同种免疫性新生儿中性粒细胞减少症。这种疾病通常是良性的,但当伴有严重感染时,可能需要进行换血输血和输注不含免疫冲突所涉及抗原的粒细胞。由于后续妊娠有复发风险,必须对随后出生婴儿的血常规进行监测。