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糖尿病并发症与民族药用植物抗糖尿病潜力洞察:综述

Diabetic Complications and Insight into Antidiabetic Potentialities of Ethno- Medicinal Plants: A Review.

作者信息

Bilal Muhammad, Iqbal Muhammad S, Shah Syed B, Rasheed Tahir, Iqbal Hafiz M N

机构信息

State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.

Health Biotechnology Laboratory, Department of Bioinformatics & Biotechnology, Government College University, Faisalabad, Pakistan.

出版信息

Recent Pat Inflamm Allergy Drug Discov. 2018;12(1):7-23. doi: 10.2174/1872213X12666180221161410.

DOI:10.2174/1872213X12666180221161410
PMID:29473531
Abstract

BACKGROUND

The naturally inspired treatment options for several disease conditions and human-health related disorders such as diabetes mellitus have gained considerable research interest. In this context, naturally occurring plants and herbs with medicinal functionalities have gained special place than ever before in the current medicinal world.

OBJECTIVE

The objective of this review is to extend the current knowledge in the clinical field related to the diabetic complications. A special focus has also been given to the anti-diabetic potentialities of ethnomedicinal plants.

METHOD

Herein, we reviewed and compiled salient information from the authentic bibliographic databases including PubMed, Scopus, Elsevier, Springer, Bentham Science and other scientific databases. The patents were searched and reviewed from http://www.freepatentsonline.com.

RESULTS

Diabetes mellitus is a group of metabolic disorders associated with the endocrine system that resulted in hyperglycemic conditions. Metabolic disorders can cause many complications such as neuropathy, retinopathy, nephropathy, ischemic heart disease, stroke, and microangiopathy. Traditional botanical therapies have been used around the world to treat diabetes. Among several medications and different medicines, various herbs are known to cure and control diabetes; also have no side effects. History has shown that medicinal plants have long been used for traditional healing around the world to treat diabetes. More than 800 plants around the world are shown by ethnobotanical information as traditional remedies for the treatment of diabetes. Several parts of these plants have been evaluated and appreciated for hypoglycemic activity. Medicinal plants have been found to be more effective than conventional drug compounds with no/fewer side effects and relatively inexpensive. In this review paper, we have reviewed plants with anti-diabetic and related beneficial medicinal effects.

CONCLUSION

This review may be helpful for researchers, diabetic patient and decision makers in the field of ethnobotanical sciences. These efforts may also provide treatment to everyone and focus on the role of traditional novel medicine plants that have anti-diabetic abilities.

摘要

背景

针对多种疾病状况以及与人类健康相关的疾病(如糖尿病),受自然启发的治疗方案已引起了相当大的研究兴趣。在此背景下,具有药用功能的天然植物和草药在当今医药领域获得了前所未有的特殊地位。

目的

本综述的目的是扩展临床领域中与糖尿病并发症相关的现有知识。同时也特别关注了民族药用植物的抗糖尿病潜力。

方法

在此,我们从包括PubMed、Scopus、爱思唯尔、施普林格、本特姆科学等权威文献数据库以及其他科学数据库中回顾并汇编了重要信息。从http://www.freepatentsonline.com搜索并审查了相关专利。

结果

糖尿病是一组与内分泌系统相关的代谢紊乱疾病,会导致血糖升高。代谢紊乱会引发许多并发症,如神经病变、视网膜病变、肾病、缺血性心脏病、中风和微血管病变。传统植物疗法已在世界各地用于治疗糖尿病。在多种药物和不同药品中,已知多种草药可治愈和控制糖尿病,且无副作用。历史表明,药用植物长期以来在世界各地被用于传统治疗糖尿病。民族植物学信息显示,全球有800多种植物是治疗糖尿病的传统药物。这些植物的多个部位已被评估并因其降血糖活性而受到认可。已发现药用植物比传统药物化合物更有效,且无/副作用更少且相对便宜。在这篇综述文章中,我们回顾了具有抗糖尿病及相关有益药用效果的植物。

结论

本综述可能对民族植物科学领域的研究人员、糖尿病患者和决策者有所帮助。这些努力也可能为每个人提供治疗,并关注具有抗糖尿病能力的传统新型药用植物的作用。

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