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男性心血管疾病一级预防的危险因素控制:来自阿拉贡工人健康研究(AWHS)的证据。

Risk factors control for primary prevention of cardiovascular disease in men: Evidence from the Aragon Workers Health Study (AWHS).

机构信息

Preventive Medicine and Public Health Department, Zaragoza University, Zaragoza, Spain.

Aragon Institute for Health Research (IIS Aragón), Zaragoza, Spain.

出版信息

PLoS One. 2018 Feb 23;13(2):e0193541. doi: 10.1371/journal.pone.0193541. eCollection 2018.

Abstract

Benefits of cardiovascular disease (CVD) risk factors control are well known, but goals achievement remains low. The objective of this study is to evaluate the prevalence of CVD risk factors among men ina worker's cohort with no previous CVD, to study control variations across time and the factors associated with poor control. To this end, we conducted a cohort reexamination (2010-2014) within the context of the Aragon Workers Health Study (AWHS). Data from working characteristics, analytical values and pharmacological prescription were included in the analysis. Prevalences of risk factor diagnosis and control were calculated, as well as factors associated with poor control. The prevalence of CVD risk factors was high. In 2014dyslipidaemia was the most prevalent (85.2%) followed by Hypertension (HT) (42.0%). People under treatment increased for the period analysed (p<0.001). The proportion of people treated varied from 72.2% in Diabetes Mellitus to 31.1% in dyslipidaemia in 2014. 46.2% of the workers with HT were controlled, decreasing to 21.9% in Diabetes and 11.0% in dyslipidaemia (2014). Working in a turn different to central shift was associated with poor control, especially for those working at night with HT (Odds Ratio in 2010: 3.6; Confidence Interval 95% 1.8-7.4) and dyslipidaemia (Odds Ratio 2010: 4.7; Confidence Interval 95% 1.3-16.4). We conclude that, although CVD control has increased significantly for the period studied, there are still many people that do not receive any treatment, and control goals are normally not achieved.

摘要

心血管疾病(CVD)风险因素的控制益处众所周知,但目标的实现率仍然较低。本研究的目的是评估无先前 CVD 的男性工人队列中 CVD 风险因素的流行程度,研究随时间的控制变化以及与控制不良相关的因素。为此,我们在阿拉贡工人健康研究(AWHS)的背景下进行了队列复查(2010-2014 年)。分析中包括工作特征、分析值和药物处方的数据。计算了风险因素诊断和控制的流行率,以及与控制不良相关的因素。CVD 风险因素的患病率很高。2014 年,血脂异常是最常见的(85.2%),其次是高血压(HT)(42.0%)。接受治疗的人数在分析期间有所增加(p<0.001)。2014 年,接受治疗的人数从糖尿病的 72.2%到血脂异常的 31.1%不等。HT 患者中有 46.2%得到控制,糖尿病患者降至 21.9%,血脂异常患者降至 11.0%(2014 年)。与中央班次不同的轮班工作与控制不良相关,尤其是夜间工作的 HT 患者(2010 年的优势比:3.6;95%置信区间 1.8-7.4)和血脂异常(2010 年的优势比:4.7;95%置信区间 1.3-16.4)。我们的结论是,尽管研究期间 CVD 控制显著增加,但仍有许多人未接受任何治疗,且通常无法达到控制目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0495/5825136/929c4aedc189/pone.0193541.g001.jpg

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