Dumbryte Irma, Vebriene Jurate, Linkeviciene Laura, Malinauskas Mangirdas
Vilnius Research Group, Polocko, Lithuania.
Denta Sana, Kestucio, Lithuania.
Eur J Orthod. 2018 Nov 30;40(6):636-648. doi: 10.1093/ejo/cjx102.
To evaluate and compare the enamel microcracks (EMCs) characteristics (qualitative and quantitative) in the form of tooth damage before and after debonding from human teeth of in vitro studies.
Laboratorial studies evaluating EMCs characteristics before and after debonding metal and ceramic brackets from human teeth with intact buccal enamel.
An electronic search of four databases (all databases of the Cochrane Library, CA Web of Science, MEDLINE via PubMed, and Google Scholar) and additional manual searches were carried out, without language restrictions. Studies published between 2000 and 2017 years were selected. Reference lists of the included articles were screened, and authors were contacted when necessary.
The following six parameters were analyzed: blinding of examiner and outcome assessment, incomplete outcome data before bonding and after debonding, selective outcome reporting, and incomplete reporting of EMCs assessment.
Out of 430 potentially eligible studies, 259 were screened by title and abstract, 180 were selected for full-text analysis, 14 were included in the systematic review. Seven studies were selected for the meta-analysis.
The results for EMCs characteristics were expressed as mean differences (MDs) with their 95 per cent confidence intervals (CIs), and calculated from random-effects meta-analyses. Debonding was associated with the increase in number (three studies, MD = 3.50, 95% CI, 2.13 to 4.87, P < 0.00001), length (seven studies, MD = 3.09 mm, 95% CI, 0.75-5.43, P < 0.00001), and width (three studies, MD = 0.39 µm, 95% CI, -0.01 to 0.79, P = 0.06) of EMCs. Considerable statistical heterogeneity was found for two forest plots evaluating the changes of number and length characteristics during debonding.
There is weak evidence indicating length and width of EMCs increase following bracket removal and the scientific evidence concerning quantitative evaluation of the number parameter before and after debonding is insufficient. However, there is a strong evidence that after debonding the number of EMCs is likely to increase.
No registration was performed.
评估并比较体外研究中人类牙齿脱粘前后牙齿损伤形式的牙釉质微裂纹（EMCs）特征（定性和定量）。
评估完整颊侧牙釉质的人类牙齿上金属和陶瓷托槽脱粘前后EMCs特征的实验室研究。
对四个数据库（Cochrane图书馆的所有数据库、CA科学网、通过PubMed的MEDLINE以及谷歌学术）进行电子检索，并进行额外的手工检索，无语言限制。选取2000年至2017年间发表的研究。筛选纳入文章的参考文献列表，必要时与作者联系。
分析以下六个参数：检查者和结果评估的盲法、粘结前和脱粘后不完整的结果数据、选择性结果报告以及EMCs评估的不完整报告。
在430项潜在符合条件的研究中，通过标题和摘要筛选出259项，选择180项进行全文分析，14项纳入系统评价。7项研究纳入荟萃分析。
EMCs特征的结果以平均差（MDs）及其95%置信区间（CIs）表示，通过随机效应荟萃分析计算得出。脱粘与EMCs数量增加（三项研究，MD = 3.50，95%CI，2.13至4.87，P < 0.00001）、长度增加（七项研究，MD = 3.09 mm，95%CI，0.75 - 5.43，P < 0.00001）和宽度增加（三项研究，MD = 0.39 µm，95%CI， - 0.01至0.79，P = 0.06）相关。在评估脱粘过程中数量和长度特征变化的两个森林图中发现了相当大的统计异质性。
有微弱证据表明托槽去除后EMCs的长度和宽度增加，关于脱粘前后数量参数定量评估的科学证据不足。然而，有强有力的证据表明脱粘后EMCs的数量可能会增加。
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