Ahmed Shoaib, Ssaeed-Ul-Hassan Syed, Islam Muhammad, Qureshi Fatima, Waheed Iimran, Munawar Ittique, Ishtiaq Saiqa, Rasool Shahid, Akhtar Muhammad Furqan, Chishti Sajd Ali, Shabbir Maryam, Raza Moosa, Amir Khuram, Sharif Ali
Acta Pol Pharm. 2017 Jan;74(1):173-178.
Pistacia khinjuk is one of the fifteen known species of Pistacia belonging to Anacardiaceae family. Keeping in view the possible therapeutic utility of this genus and the lack of literature on this plant, this study involves phytochemical investigation of P. khinjuk and its antioxidant activity. The phytochemical investigation was conducted on crude methanolic extract and its fractions namely, n-hexane, chloroform, n-butanol, ethyl acetate and aqueous. Total phenolic contents and flavonoids were also determined by phosphomolybdenum and ferric thiocyanate method in crude extract and its fractions. The results of phytochemical investigation indicated the presence of alkaloids, tannins, flavonoids, saponins, triterpenoids, cardiac glycosides, carbohydrates, proteins and sterols in the crude extract of P. khinjuk. Crude extract and its fractions exhibited remarkable antioxidant activity. This study showed that the crude extract and its fractions have potent antioxidant activity, among all ethyl acetate showed 1.109 ± 0.029 the highest activity. This research concluded that crude extract of P. khinjuk and its fractions contained phenolic and flavonoid compounds that show significant antioxidant activity.
乳香黄连木是漆树科已知的15种黄连木属植物之一。鉴于该属植物可能的治疗用途以及关于这种植物的文献匮乏，本研究对乳香黄连木进行了植物化学研究及其抗氧化活性研究。对粗甲醇提取物及其馏分（正己烷、氯仿、正丁醇、乙酸乙酯和水相）进行了植物化学研究。还通过磷钼酸法和硫氰酸铁法测定了粗提取物及其馏分中的总酚含量和黄酮类化合物含量。植物化学研究结果表明，乳香黄连木粗提取物中存在生物碱、单宁、黄酮类化合物、皂苷、三萜类化合物、强心苷、碳水化合物、蛋白质和甾醇。粗提取物及其馏分表现出显著的抗氧化活性。本研究表明，粗提取物及其馏分具有强大的抗氧化活性，其中乙酸乙酯表现出最高活性，为1.109±0.029。本研究得出结论，乳香黄连木粗提取物及其馏分含有酚类和黄酮类化合物，具有显著的抗氧化活性。
