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台湾耐甲氧西林金黄色葡萄球菌 8 型(USA300)的出现、传播和系统发生

Emergence, transmission and phylogeny of meticillin-resistant Staphylococcus aureus sequence type 8 (USA300) in Taiwan.

机构信息

Division of Paediatric Infectious Diseases, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, Taiwan.

Division of Paediatric Infectious Diseases, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Chang Gung University College of Medicine, Taoyuan, Taiwan.

出版信息

J Hosp Infect. 2018 Nov;100(3):355-358. doi: 10.1016/j.jhin.2018.02.014. Epub 2018 Feb 21.

DOI:10.1016/j.jhin.2018.02.014
PMID:29475012
Abstract

Twenty-seven (0.51%) USA300 isolates were identified from a pool of 5308 meticillin-resistant Staphylococcus aureus (MRSA) isolates collected in Taiwan between 1995 and October 2015, including 12 infecting isolates from 10 patients. The first two isolates were identified in 2005, and 23 isolates have been collected since 2010. Phylogenetic analysis revealed that all the local isolates were closely related to those in North America, and there was a clade consisting of 13 local isolates from 10 patients. MRSA USA300 existed in Taiwan in 2005 or earlier, with increasing identification since 2010. Local transmission of USA300 has occurred in Taiwan after importation from North America.

摘要

从 1995 年至 2015 年 10 月期间在台湾收集的 5308 株耐甲氧西林金黄色葡萄球菌(MRSA)分离株的群体中,鉴定出 27 株(0.51%)USA300 分离株,包括来自 10 位患者的 12 株感染性分离株。前两株分离株于 2005 年鉴定,自 2010 年以来已收集了 23 株分离株。系统发育分析显示,所有本地分离株与北美的分离株密切相关,存在一个由来自 10 位患者的 13 株本地分离株组成的分支。2005 年或更早以前,MRSA USA300 就在台湾存在,自 2010 年以来,其鉴定数量不断增加。MRSA USA300 是从北美输入后在台湾发生本地传播的。

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