在纳米级通信中，尺寸很重要。
Size matters in nanoscale communication.
机构信息
Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Program in Cancer Biology, Vanderbilt University Medical Center, Nashville, TN, USA.
出版信息
Nat Cell Biol. 2018 Mar;20(3):228-230. doi: 10.1038/s41556-018-0049-8.
Abstract
Exosomes are heterogeneous, nanoscale vesicles that mediate cellular communication. A study now leverages a size separation strategy to identify sub-classes of nanoparticles. Besides revealing a subtype without an encapsulating membrane, biochemical analyses show variation in vesicle cargo, suggesting that size is not the only driver of heterogeneity.
摘要
外泌体是具有异质性的纳米级囊泡，可介导细胞间通讯。一项新研究利用尺寸分离策略来鉴定纳米颗粒的亚类。除了鉴定出一种没有包膜的亚型外，生化分析还显示囊泡货物存在差异，这表明尺寸并不是异质性的唯一驱动因素。
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