Hartter E, Pacher R, Frass M, Woloszczuk W, Leithner C
Klin Wochenschr. 1986;64 Suppl 6:112-4.
Circulating amounts of human atrial natriuretic peptide (hANP) are elevated in congestive heart failure and renal failure. Stretching of cardiac atria, due to volume expansion associated with these diseases, is widely accepted to be the predominant stimulus for release of the hormone. Measurements of hemodynamic parameters as well as plasma concentrations of ANP in the right cardiac atrium, pulmonary artery, radial artery and vena cava superior, before and after continuous veno-venous hemofiltration (CVVH) of critically ill volume expanded patients, proved that ANP might be a useful indicator of fluid balance in these patients.
在充血性心力衰竭和肾衰竭患者中，循环中的人心房利钠肽（hANP）水平会升高。与这些疾病相关的容量扩张导致心脏心房拉伸，这被广泛认为是该激素释放的主要刺激因素。对重症容量扩张患者进行持续静脉 - 静脉血液滤过（CVVH）前后，测量其右心房、肺动脉、桡动脉和上腔静脉的血流动力学参数以及ANP的血浆浓度，结果证明ANP可能是这些患者液体平衡的一个有用指标。
