Saffir J S
Am J Occup Ther. 1978 Aug;32(7):460-6.
In order to evaluate the influence of antipsychotic drugs used in the treatment of schizophrenia on therapy based on sensory integrative theory, this study, developed through library research, explores the theoretical bases for these two modes of treatment. Studies of chlorpromazine, a prototypical antipsychotic drug, show that its local action on the neurotransmitters of the brain may explain in theory its therapeutic efficacy. By citing evidence of sensory processing deficits in schizophrenic patients, a theoretical basis for the use of a sensory integrative approach to therapy is established. A comparison of these theories leads to the conclusion that a sensory integrative approach can serve as an important reinforcer of the therapeutic actions of chlorpromazine. Implications for treatment and research are considered.
为了评估用于治疗精神分裂症的抗精神病药物对基于感觉统合理论的治疗的影响，本研究通过文献研究开展，探索这两种治疗模式的理论基础。对典型抗精神病药物氯丙嗪的研究表明，其对大脑神经递质的局部作用在理论上可以解释其治疗效果。通过引用精神分裂症患者感觉加工缺陷的证据，建立了使用感觉统合疗法的理论基础。对这些理论进行比较后得出结论，感觉统合疗法可以作为氯丙嗪治疗作用的重要强化手段。文中还考虑了对治疗和研究的启示。
