From the Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Department of Pediatric Surgery, Bangladesh Institute of Research and Rehabilitation for Diabetes, Endocrine, and Metabolic Disorders-II Hospital, Dhaka, Bangladesh.
Anesth Analg. 2018 May;126(5):1684-1686. doi: 10.1213/ANE.0000000000002865.
Respiratory distress syndrome remains a leading cause of neonatal mortality worldwide. This retrospective study describes practice patterns for respiratory distress syndrome in a resource-limited setting and seeks to identify both risk factors for mortality and beneficial treatment modalities. Health, demographic, and treatment data were collected. Potential associations were analyzed using univariable and multivariable logistic regression. Of 104 children included for analysis, 38 died. Although most children were initially treated with noninvasive respiratory support, 59 progressed to invasive ventilation. Requirement for invasive ventilation was associated with death. A clear trend toward improved survival in mechanically ventilated patients was seen with surfactant administration.
新生儿呼吸窘迫综合征仍然是全球新生儿死亡的主要原因。本回顾性研究描述了资源有限环境下新生儿呼吸窘迫综合征的治疗模式,并试图确定其死亡率的相关因素和有益的治疗方法。收集了健康、人口统计学和治疗数据。使用单变量和多变量逻辑回归分析潜在的关联。在纳入分析的 104 名儿童中,有 38 名死亡。尽管大多数儿童最初接受了无创呼吸支持,但仍有 59 例进展为有创通气。需要有创通气与死亡相关。接受表面活性剂治疗的机械通气患者的生存率有明显改善的趋势。