Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, School of Pharmacy, Nanjing 211198, Jiangsu Province, PR China.
Department of Physical Education, Shaanxi Normal University, Xian 710062, Shaanxi Province, PR China.
Biomed Pharmacother. 2018 Apr;100:521-531. doi: 10.1016/j.biopha.2018.02.048. Epub 2018 Feb 23.
Medicinal plants are essential parts of traditional medicine due to their phytochemical constituents having pharmacological values and therapeutic applications. Black tea have thousands of various biological compounds such as flavonoids (Thearubigins (TRs) and theaflavins (TFs) and catechins), amino acids (L.theanine), vitamins (A, C, K), phenolic acids (caffeic acid (CA), gallic acid (GA), chlorogenic acids (CGA) and cauramic acid), lipids, proteins, volatile compounds carbohydrates, β-carotene and fluoride that illustrated many promising pharmacological effects regarded as growth promoter, cardioprotector, potent cholesterol-lowering effect, antioxidant and antimicrobial, etc inhuman. Although there is an exponential growth in molecular evidence of cholesterol-lowering and antioxidant effect in human, there is still a lack of information of the pharmacological effects of black tea. To fill this information gap, therefore, this review article underscores broadening the new insight pertaining to black tea that could be used as safe food additive. This article also illuminates the interesting role of black tea as an herbal medicine that is the future demand to get rid of synthetic health promoters in the human health practice. Moreover, this information would be useful in terms of the low-cost practice of natural medicines with no residual effects, and a natural protection of the human being. In addition, further studies at a molecular level are needed to reveal its mechanism of action particularly for the hypocholesterolemic effect of black tea to overcome the heart-related diseases, fewer side effects and being a natural safeguard of human health.
药用植物是传统医学的重要组成部分,因为它们的植物化学成分具有药理学价值和治疗应用。红茶含有数千种不同的生物化合物,如类黄酮(茶红素 (TRs) 和茶黄素 (TFs) 和儿茶素)、氨基酸(L-茶氨酸)、维生素(A、C、K)、酚酸(咖啡酸 (CA)、没食子酸 (GA)、绿原酸 (CGA) 和咖啡鞣酸)、脂类、蛋白质、挥发性化合物碳水化合物、β-胡萝卜素和氟化物,这些物质表现出许多有前途的药理学作用,被认为是生长促进剂、心脏保护剂、强效降胆固醇作用、抗氧化剂和抗菌剂等。尽管在人类中降低胆固醇和抗氧化作用的分子证据呈指数增长,但仍缺乏红茶的药理学作用的信息。为了填补这一信息空白,因此,本文综述强调了拓宽与红茶相关的新见解,可以将其用作安全的食品添加剂。本文还阐明了红茶作为草药的有趣作用,这是未来摆脱人类健康实践中合成健康促进剂的需求。此外,从无残留效果的低成本天然药物实践和对人类的天然保护的角度来看,这些信息将是有用的。此外,还需要在分子水平上进行进一步的研究,以揭示其作用机制,特别是红茶的降胆固醇作用,以克服与心脏相关的疾病,减少副作用,并成为人类健康的天然保障。