Zamotin B A, Kravtsov F E, Naumovich L S, Zhdanov G P, Averina G A
Zh Mikrobiol Epidemiol Immunobiol. 1986 Nov(11):20-4.
In recent years the tendency towards the activation of the epidemic process of diphtheria, i.e. the appearance of cases of diphtheria simultaneously with the increased levels of circulation of toxigenic and nontoxigenic Corynebacterium diphtheriae and with antitoxic immunity characteristics in children and adults constantly remaining low, has been registered. For the effective control of diphtheria, the profound study of such problems as bacterial carriership, antibacterial immunity and the development of supplementary means of specific prophylaxis is necessary.
近年来,已记录到白喉流行过程有激活的趋势,即白喉病例出现的同时,产毒和不产毒白喉棒状杆菌的传播水平增加,且儿童和成人的抗毒免疫力持续处于低水平。为有效控制白喉,有必要深入研究诸如带菌状态、抗菌免疫以及开发特异性预防补充手段等问题。